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2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a food-derived carcinogen that is found in high temperature-cooked fish and meat. In humans, PhIP is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts, which are directly correlated with increased risk of breast, colon, and prostate cancers. Synonyms: PhIP; 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine. Grades: ≥98%. CAS No. 105650-23-5. Molecular formula: C13H12N4. Mole weight: 224.3. BOC Sciences 10
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP). Group: Biochemicals. Alternative Names: 1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine; PhIP. Grades: Highly Purified. CAS No. 105650-23-5. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 224.26. US Biological Life Sciences. USBiological 1
Worldwide
PhIP PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat [1] [2]. DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. CAS No. 105650-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118716. MedChemExpress MCE

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