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Takinib Takinib (EDHS-206) is an orally active and selective TAK1 inhibitor (IC50=9.5 nM), more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib is an inhibitor of autophosphorylated TAK1 that non-competitively binds within the ATP binding pocket. Takinib induces apoptosis following TNF? stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is also a P. falciparum protein kinase 9 (PfPK9) inhibitor (KD(app) of 0.46 ?M)[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EDHS-206. CAS No. 1111556-37-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103490. MedChemExpress MCE
Takinib Takinib Inhibitor. Uses: Scientific use. Product Category: T4264. CAS No. 1111556-37-6. TARGETMOL CHEMICALS

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