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An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. Group: Fluorescence/luminescence spectroscopy.
1,1-Dimethylbiguanide hydrochloride
1,1-Dimethylbiguanide hydrochloride is the hydrochloride salt of the biguanide metformin with antihyperglycemic and potential antineoplastic activities. It decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Uses: Hypoglycemic agents. Synonyms: Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1); Biguanide, 1,1-dimethyl-, hydrochloride; Biguanide, 1,1-dimethyl-, monohydrochloride; Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride; Apo-Metformin; Apophage; Benofomin; Brot; Dabex; Denkaform; Fornidd; Geamet; Glifage; LA 6023; Meguan; Metformin hydrochloride; N,N-Dimethylbiguanide hydrochloride; N1,N1-Dimethylbiguanide hydrochloride; Nelbis; Neodipa; Obimat-SR; Orabet; Riomet; Siamformet; Walaphage. CAS No. 1115-70-4. Molecular formula: C4H12ClN5. Mole weight: 165.62.
25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C4H11N5 ·HCl. CAS No. 1115-70-4. Prepack ID 26472003-25g. Molecular Weight 165.62. See USA prepack pricing.
Metformin hydrochloride
Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, metformin hydrochloride regulates the expression of autophagy -related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,1-Dimethylbiguanide hydrochloride. CAS No. 1115-70-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-17471A.
Metformin hydrochloride
Metformin hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1-Dimethyl-biguanidhydrochloride. Appearance: White powder. CAS No. 1115-70-4. Molecular formula: C4H12ClN5. Mole weight: 165.62. Purity: 0.99. IUPACName: 3-(Diaminomethylidene)-1,1-dimethylguanidine;hydrochloride. Canonical SMILES: CN(C)C(=N)N=C(N)N.Cl. Density: 1.36 g/cm³ at 20 °C. Product ID: ACM1115704. Alfa Chemistry ISO 9001:2015 Certified.
Metformin Hydrochloride
Inhibits hepatic gluconeogenesis by activating AMP-activated protein kinase (AMPK). A widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. Anti-cancer activity of metformin has been attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation. Group: Biochemicals. Alternative Names: N, N-Di methyl imidodicarbonimidic Diamide Hydrochloride; Diabetosan; Diabex; Glucophage; Metiguanide; Glucoform; Glucomet; Glucomin; Glucomine; Orabet; Siamformet; Walaphage; Glumetza. Grades: Highly Purified. CAS No. 1115-70-4. Pack Sizes: 10g, 50g, 100g. Molecular Formula: C4H12ClN5, Molecular Weight: 165.62. US Biological Life Sciences.
Worldwide
Metformin (hydrochloride) (Standard)
Metformin hydrochloride (Standard) is the analytical standard of Metformin (hydrochloride). This product is intended for research and analytical applications. Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, metformin hydrochloride regulates the expression of autophagy -related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,1-Dimethylbiguanide (hydrochloride) (Standard). CAS No. 1115-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17471AR.
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