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Pf 184 Pf 184. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PF 184, NCGC00263213-01, FT-0673646, 1187460-81-6, 8-[[[5-Chloro-2-[3,4-dimethyl-3,4-bis(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxamide. Product Category: Heterocyclic Organic Compound. CAS No. 1187460-81-6. Molecular formula: C32H32ClFN6O4. Mole weight: C32H32ClFN6O4. Purity: >98 %. IUPACName: 8-[[2-[(3S,4R)-3,4-bis(hydroxymethyl)-3,4-dimethylpyrrolidin-1-yl]-5-chloropyridine-4-carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydrobenzo[g]indazole-3-carboxamide. Canonical SMILES: CC1(CN(CC1(C)CO)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl)CO. Product ID: ACM1187460816. Alfa Chemistry — ISO 9001:2015 Certified. Categories: PF-184563. Alfa Chemistry. 5
PF184 PF184. CAS No: 1187460-81-6 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
PF 184 PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1 β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress. Group: Biochemicals. Alternative Names: 8- [ [ [5-Chloro-2- [3, 4-dimethyl-3, 4-bis (hydroxymethyl) -1-pyrrolidinyl] -4-pyridinyl] carbonyl] amino] -1- (4-fluorophenyl) -4, 5-dihydro-1H-benz [g] indazole-3-carboxamide. Grades: Highly Purified. CAS No. 1187460-81-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
PF 184 PF 184 is a potent and selective IKKβ inhibitor (IC50 = 37 nM) with selectivity over 85 other kinases, demonstrating target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation. Synonyms: 8-[[[5-Chloro-2-[3,4-dimethyl-3,4-bis(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxamide; PF-184; PF184; PF 184. Grades: ≥98% by HPLC. CAS No. 1187460-81-6. Molecular formula: C32H32ClFN6O4. Mole weight: 619.09. BOC Sciences 10

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