Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| GDC-0575 | GDC-0575 is a highly-selective, potent and oral small-molecule Chk1 inhibitor (IC50 = 1.2?nM). Uses: Protein kinase inhibitors. Synonyms: ARRY-575; RG7741; GDC0575. Grades: ≥98%. CAS No. 1196541-47-5. Molecular formula: C16H20BrN5O. Mole weight: 378.27. |  |
| GDC-0575 freebase | GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476; GDC-0575 HCl; GDC-0575 hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1196541-47-5. Molecular formula: C16H20BrN5O. Mole weight: 378.27. Purity: >98%. IUPACName: (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide. Canonical SMILES: O=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32. Product ID: ACM1196541475. Alfa Chemistry ISO 9001:2015 Certified. |  |
Our database is helping our users find suppliers everyday.
