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| Product | Description | |
|---|---|---|
| PF-04856264 | This active molecular is a human Nav1.7 voltage gated sodium channel inhibitor with the IC50 value of 28 nM. PF-04856264 inhibits the Nav channel by interacting with the S1-S4 voltage sensor segment of homologous domain 4 which is unlike other known NaV inhibitors. PF-04856264 interaction with the region of the channel which controls voltage sensitivity enables subtype selective modulation and may be applicated as an efficient tool for drug development. Synonyms: PF-04856264; PF04856264; PF 04856264; PF-4856264; PF4856264; PF 4856264. 3-cyano-4-(2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-N-(thiazol-2-yl)benzenesulfonamide. Grades: 98%. CAS No. 1235397-05-3. Molecular formula: C20H15N5O3S2. Mole weight: 437.49. |  |
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