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| Product | Description | |
|---|---|---|
| 3-[2-[[3-Fluoro-4- (4-methyl-1-piperazinyl) phenyl]amino]-5-methyl-7H-pyrrolo[2, 3-d]pyrimidin-4-yl]benzeneacetonitrile | 3-[2-[[3-Fluoro-4- (4-methyl-1-piperazinyl) phenyl]amino]-5-methyl-7H-pyrrolo[2, 3-d]pyrimidin-4-yl]benzeneacetonitrile is an anticancer agent and a selective Axl inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1239875-86-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C26H26FN7, Molecular Weight: 455.53. US Biological Life Sciences. |  Worldwide |
| SGI-7079 | SGI-7079 Inhibitor. Uses: Scientific use. Product Category: T6982. CAS No. 1239875-86-5. |  |
| SGI-7079 | This active molecular is a selective Axl inhibitor and Axl is a potential therapeutic target for overcoming EGFR inhibitor resistance. SGI-7079 significantly inhibits the proliferation of SUM149 or KPL-4 cells. IC50 value for SUM149 is 0.43 μM, 0.16 μM for KPL-4. It inhibited Axl activation in the presence of exogenous Gas6 ligand effectively. It will be a drug candidate as a anticancer agent. Uses: Anti-cancer. Synonyms: SGI-7079; SGI 7079; SGI7079. 2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile. CAS No. 1239875-86-5. Molecular formula: C26H26FN7. Mole weight: 455.53. |  |
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