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| Product | Description | |
|---|---|---|
| Alectinib Hydrochloride | Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC 50 of 1.9 nM and a K d value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC 50 s of 1 nM and 3.5 nM, respectively [1]. Alectinib demonstrates effective central nervous system (CNS) penetration [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride. CAS No. 1256589-74-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13011A. |  |
| CH5424802 Hydrochloride | CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Synonyms: Alectinib Hydrochloride; AF-802 Hydrochloride; CH-5424802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; AF 802 Hydrochloride; CH 5424802 Hydrochloride; RG 7853 Hydrochloride; RO 5424802 Hydrochloride; AF802 Hydrochloride; CH5424802 Hydrochloride; RG7853 Hydrochloride; RO5424802 Hydrochloride. Grades: >98%. CAS No. 1256589-74-8. Molecular formula: C30H35ClN4O2. Mole weight: 519.08. |  |
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