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Product | Description | |
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Colistin sulfate Quick inquiry Where to buy Suppliers range | Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa. Synonyms: Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin. Grades: ≥95%. CAS No. 1264-72-8. Molecular formula: Colistin A: C53H100N16O13; Colistin B: C52H98N16O13. Mole weight: Colistin A: 1169.46; Colistin B: 1155.43. | |
Colistin Sulfate Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C52H98N16O13. CAS No. 1264-72-8. Prepack ID 49952997-1g. Molecular Weight 1155.43. See USA prepack pricing. | |
Colistin Sulfate Quick inquiry Where to buy Suppliers range | 5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C52H98N16O13. CAS No. 1264-72-8. Prepack ID 49952997-5g. Molecular Weight 1155.43. See USA prepack pricing. | |
Colistin Sulfate Quick inquiry Where to buy Suppliers range | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C52H98N16O13. CAS No. 1264-72-8. Prepack ID 49952997-100mg. Molecular Weight 1155.43. See USA prepack pricing. | |
Colistin Sulfate (Mixture of A and B compound) Quick inquiry Where to buy Suppliers range | Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistin A and B.Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic. Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter.[1] New Delhi metallo- β-Lactamase multidrug-resistant Enterobacteriaceae have also shown susceptibility to Colistin.[2]Colistin is polycationic and has both hydrophilic and lipophilic moieties. These poly-cationic regions interact with the bacterial outer membrane, by displacing bacterial counter ions in the lipopolysaccharide. Hydrophobic / hydrophillic regions interact with the cytoplasmic membrane just like a detergent, solubilizing the membrane in an aqueous environment. This effect is bactericidal even in an isosmolaric environment.Resistance to colistin is currently rare, but is described. At present there is no agreement about how to look for colistin resistance. The Société Française de Microbiologie uses a cut off of 2 mg/l, whereas the British Society for Antimicrobial Chemotherapy sets a cutoff of 4 mg/l or less as sensitive, and 8 mg/ml or more as resistant. There are not currently any US standards for measuring colistin sensitivity. Exceptional (inherently colistin resistant) Gram-negative bacteria: BrucellaBurkholderia cepaciaChryseobacteriu m indologen esEdwardsiel laElizabethkingia meningosepticaFrancise lla tularensis spp.Gram-negative cocciHelicobacter pyloriMoraxella catarrhalisNeisseria gonorrheae and Neisseria meningitidisProteusPro vide nciaSerratiaSome strains of Stenotrophomonas maltophilia[18]Gram-negative organisms with variable resistance to colistin: AeromonasVib rioPrevotellaFusobacte rium . Group: Biochemicals. Alternative Names: Polymyxin E. sulfate; Belcomycine; Colomycin. Grades: Highly Purified. CAS No. 1264-72-8. Pack Sizes: 250mg, 1g, 5g, 10g. Molecular Formula: x(C??H???N??O??)? + x(C ??H??N??O??)B.xH?, Molecular Weight: 1169.46. US Biological Life Sciences. | Worldwide |
Colistin Sulphate Salt Quick inquiry Where to buy Suppliers range | Colistin Sulphate Salt. CAS No. 1264-72-8. Ebrator Biochemicals provides scientists around the global scientific community with a wide range of high purity Life Science products & Fine Chemicals. |