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| Product | Description | |
|---|---|---|
| S1RA hydrochloride | S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor ( σ1R ) antagonist with a K i value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (K i >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC 50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862 hydrochloride. CAS No. 1265917-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-18099A. |  |
| S1RA Hydrochloride | The hydrochloride salt form of S1RA which is a σ1 receptor antagonist that has been found to have potential effect in pain therapy. It is still under Phase II clinical trial. IC50: 17 nM (Ki). Uses: The hydrochloride salt form of s1ra which is a σ1 receptor antagonist that has been found to have potential effect in pain therapy. Synonyms: S1RA hydrochloride; S1RA (hydrochloride); E-52862 hydrochloride; E 52862 hydrochloride; E52862 hydrochloride; SCHEMBL99116; UNII-18XZ7850YN. Grades: 98%. CAS No. 1265917-14-3. Molecular formula: C20H24ClN3O2. Mole weight: 373.88. |  |
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