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| Product | Description | |
|---|---|---|
| Pazufloxacin | Pazufloxacin (T-3761), a new quinolone derivative, showed broad and potent antibacterial activity. T-3761 showed good efficacy in mice against systemic, pulmonary, and urinary tract infections with gram-positive and gram-negative bacteria, including quinolone-resistant Serratia marcescens and Pseudomonas aeruginosa. The in vivo activity of T-3761 was comparable to or greater than those of ofloxacin, ciprofloxacin, norfloxacin, and tosufloxacin against most infection models in mice. The activities of T-3761 were lower than those of tosufloxacin against gram-positive bacterial systemic and pulmonary infections in mice but not against infections with methicillin-resistant Staphylococcus aureus. T-3761 had a broad spectrum of activity and had potent activity against gram-positive and -negative bacteria. The MICs of T-3761 against 90% of the methicillin-susceptible Staphylococcus aureus, methicillin-susceptible and -resistant Staphylococcus epidermidis, and Clostridium spp. tested were 0.39 to 6.25 micrograms/ml. The MBCs of T-3761 were either equal to or twofold greater than the MICs. The 50% inhibitory concentrations of T-3761 for DNA gyrases isolated from E. coli and P. aeruginosa were 0.88 and 1.9 micrograms/ml, respectively. Synonyms: T-3761; T3761; T 3761. Grades: >98%. CAS No. 127045-41-4. Molecular formula: C16H15FN2O4. Mole weight: 318.3. |  |
| Pazufloxacin ethyl ester | Pazufloxacin ethyl ester is an impurity of Pazufloxacin. Pazufloxacin is a fluoroquinolone antibiotic. Uses: Antitubercular agents. Synonyms: Pazufloxacin; 127045-41-4; T-3761; Pazufloxacin [INN]; 127046-18-8; 4CZ1R38NDI; DTXSID5046697; NCGC00167534-01; (-)-(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid; (2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid; 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid,10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-; DTXCID3026697;(2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid; (S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid. CAS No. 127046-18-8. Molecular formula: C18H19FN2O4. Mole weight: 346.358. | |
| Pazufloxaxin | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C16H15FN2O4. CAS No. 127045-41-4. Prepack ID 75835146-100mg. Molecular Weight 318.3. See USA prepack pricing. |  |
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