130306 02 4 Suppliers USA
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Product | Description | |
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(E) -2'-Deoxy-2'- (fluoromethylene) cytidine Quick inquiry Where to buy Suppliers range | (E) -2'-Deoxy-2'- (fluoromethylene) cytidine. Group: Biochemicals. Alternative Names: Tezacitabine. Grades: Highly Purified. CAS No. 130306-02-4. Pack Sizes: 100mg. Molecular Formula: C10H12FN3O4. US Biological Life Sciences. | Worldwide |
(E) -2'-Deoxy-2'- (fluoromethylene) cytidine Quick inquiry Where to buy Suppliers range | (E) 2' Deoxy 2' (fluoromethylene) cytidine. CAS No. 130306-02-4. | |
Tezacitabine Quick inquiry Where to buy Suppliers range | Tezacitabine is a synthetic purine nucleoside analogue with potential antineoplastic activity. Phosphorylated by cellular kinases, tezacitabine is converted into its active diphosphate and triphosphate metabolites. Tezacitabine diphosphate binds to and irreversibly inhibits the activity of the enzyme ribonucleotide reductase (RNR), which may result in the inhibition of DNA synthesis in tumor cells and tumor cell apoptosis. Tezacitabine triphosphate acts as a substrate for DNA polymerase, further compromising DNA replication. This agent is relatively resistant to metabolic deactivation by cytidine deaminase. RNR catalyzes the conversion of ribonucleoside 5'-diphosphates to deoxyribonucleoside 5'-diphosphates necessary for DNA synthesis and is overexpressed in many tumor types. Uses: Enzyme inhibitors. Synonyms: MDL 101731; FMdC; KW 2331; MDL 101731; KW2331; MDL101731; Tezacitabine; MDL 101,731; FMdC. CAS No. 130306-02-4. Molecular formula: C10H12FN3O4. Mole weight: 257.221. |