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| Product | Description | |
|---|---|---|
| Flavopiridol Hydrochloride | An inhibitor of cyclin-dependent kinases; the (-)-cis form induces apoptosis in certain tumor cells. Group: Biochemicals. Alternative Names: rel-(-)-2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one Hydrochloride; Alvocidib Hydrochloride; HL 275; MDL 107826A; NSC 649890. Grades: Highly Purified. CAS No. 131740-09-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Flavopiridol Hydrochloride | Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK , competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC 50 s of 30, 170, 100 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alvocidib Hydrochloride; L86-8275 Hydrochloride; HMR-1275 Hydrochloride. CAS No. 131740-09-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10006. |  |
| Flavopiridol Hydrochloride | Flavopiridol hydrochloride competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Synonyms: NSC 649890 HCl; NSC649890 HCl; NSC-649890 HCl. Grades: >98%. CAS No. 131740-09-5. Molecular formula: C21H20ClNO5.HCl. Mole weight: 438.3. |  |
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