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| Product | Description | |
|---|---|---|
| CAIX Inhibitor S4 | CAIX Inhibitor S4 is an inhibitor of carbonic anhydrase IX. It is selective for CAIX over CAI and CAII but does inhibit CAXII. It reduced the number of lung metastases, but not primary tumor growth, in an MDA-MB-231 mouse xenograft model. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1330061-67-0. Molecular formula: C15H17N3O4S. Mole weight: 335.38. Purity: >98%. IUPACName: 4-(3-(3,5-dimethylphenyl)ureido)phenyl sulfamate. Canonical SMILES: O=S(OC[5]=CC=C(NC(NC[16]=CC(C)=CC(C)=C@16)=O)C=C@6)(N)=O. Product ID: ACM1330061670. Alfa Chemistry ISO 9001:2015 Certified. |  |
| S4 | S4 is a high affinity and selective carbonic anhydrase CA IX and CA XII inhibitor (Ki = 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively). S4 has been shown to inhibit migration and proliferation of breast cancer cells in in vitro assays. S4 inhibits lung metastasis in mice bearing breast tumor xenografts, without affecting primary tumor. Synonyms: 4-[[[ (3, 5-Dimethylphenyl) amino]carbonyl]amino]phenyl sulfamate; CAIX Inhibitor S4. Grades: ≥99% by HPLC. CAS No. 1330061-67-0. Molecular formula: C15H17N3O4S. Mole weight: 335.38. |  |
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