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AG-490 AG-490. Group: Biochemicals. Alternative Names: 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; Tyrphostin B 42. Grades: Highly Purified. CAS No. 134036-52-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H14N2O3. US Biological Life Sciences. USBiological 6
Worldwide
(E/Z)-AG490 (E/Z)-AG490 is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Uses: A potent and specific inhibitor of the jak-2 tyrosine kinase. in acute lymphoblastic leukemia (all) cells which abundantly express jak-2, ag-490 dose-dependently inhibited dna synthesis, blocked cell growth and induced apoptosis. ag-490 does not signific. Synonyms: (E/Z)-Tyrphostin AG490; (E/Z)-Tyrphostin B42; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamide; N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide. Grade: 95%. CAS No. 134036-52-5. Molecular formula: C17H14N2O3. Mole weight: 294.30. BOC Sciences 3

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