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| Product | Description | |
|---|---|---|
| MM-102 | MM-102, as a MLL1 mimetic, shows high binding affinities to WDR5 with IC50 of 2.9 nM and Ki of < 1 nM. Synonyms: MM-102; MM102; MM 102; HMTase Inhibitor IX. Grade:>98%. CAS No. 1417329-24-8. Molecular formula: C35H49F2N7O4. Mole weight: 669.8. |  |
| MM-102 | MM-102 (HMTase Inhibitor IX) is a cell-permeable and tightly binding inhibitor of MLL1-WDR5 interaction (IC50=2.4 nM). MM-102 can specifically inhibit the growth and induce apoptosis of leukemia cells containing MLL1 fusion protein, and reduce renal fibrosis and inflammation in mice with ischemia-reperfusion injury. In addition, MM-102 also acts as an H3K4 histone methyltransferase inhibitor to improve the development of porcine somatic cell nuclear transfer (SCNT) embryos[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMTase Inhibitor IX. CAS No. 1417329-24-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12220. |  |
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