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Product | Description | |
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HIF Inhibitor VII (Hypoxia-Inducible Factor Inhibitor VI, N-(3-Chloro-5-fluorophenyl)-4-nitrobenzo[c][1, 2, 5]oxadiazol-5-amine) Quick inquiry Where to buy Suppliers range | A cell-permeable benzoxadiazolamine that prevents HIF-2alpha-HIF-beta/ARNT heterodimeration by perturbing HIF-2alpha Per-ARNT-Sim/PAS-B domain surface beta-sheet conformation via a 1:1 stoichiometric binding (KD = 81nM), while exhibiting no affinity toward HIF-1alphaPAS-B domain. Shown to be metabolically stable and non-cytotoxic in cultures and selectively inhibit hypoxia-induced HIF-2a DNA binding and HIF-2alpha-dependent EPO mRNA upregulation (1 to10uM for 6-12h), but not HIF-1alpha DNA binding or HIF-1alpha-dependent PGK1 mRNA upregulation, in Hep3B cells. Unlike HIF Inhibitors I-VI, this compound does not affect the cellular protein or mRNA levels of HIF-1alpha & HIF-2alpha. Group: Biochemicals. Grades: Highly Purified. CAS No. 1422955-31-4. Pack Sizes: 10mg. Molecular Formula: C??H?ClFN?O?, Molecular Weight: 308.65. US Biological Life Sciences. | Worldwide |
JNJ 47965567 Quick inquiry Where to buy Suppliers range | JNJ 47965567 has been found to be a selective P2X7 antagonist and is brain penetrant. Synonyms: JNJ-47965567; JNJ 47965567; JNJ47965567. 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1428327-31-4. Molecular formula: C28H32N4O2S. Mole weight: 488.64. | |
JNJ 47965567 Quick inquiry Where to buy Suppliers range | JNJ 47965567. Group: Biochemicals. Grades: Highly Purified. CAS No. 1428327-31-4. Pack Sizes: 10mg. Molecular Formula: C28H32N4O2S, Molecular Weight: 488.64. US Biological Life Sciences. | Worldwide |
Octyl Sulfate Sodium Salt Quick inquiry Where to buy Suppliers range | Octyl Sulfate Sodium Salt. CAS No. 142-31-4. Ebrator Biochemicals provides scientists around the global scientific community with a wide range of high purity Life Science products & Fine Chemicals. | |
Sodium octyl sulfate Quick inquiry Where to buy Suppliers range | Sodium octyl sulfate. Group: Biochemicals. Alternative Names: 1-Octylsodiumsulfonate. Grades: Highly Purified. CAS No. 142-31-4. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
Sodium octyl sulfate Quick inquiry Where to buy Suppliers range | Ion Pair Chromatography Reagents. Uses: For analytical and research use. Group: reagents. Grades: for ion pair chromatography. CAS No. 142-31-4. Pack Sizes: 10G. | |
Sodium Octyl Sulfate Quick inquiry Where to buy Suppliers range | Sodium Octyl Sulfate. Group: Anionic Surfactants. CAS No. 142-31-4. | |
TC-S 7009 Quick inquiry Where to buy Suppliers range | TC-S 7009 is a high affinity and selective HIF-2α inhibitor (Kd = 81 nM) that displays >60-fold selectivity for HIF-2α over HIF-1&alpha. TC-S 7009 binds to the HIF-2α PAS-B domain to disrupt HIF-2α-ARNT heterodimerization, decrease HIF-2α DNA-binding and suppress expression of HIF-2α target genes in vitro. Synonyms: TCS 7009; TC S 7009; TC-S 7009; N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine. Grades: ≥99% by HPLC. CAS No. 1422955-31-4. Molecular formula: C12H6ClFN4O3. Mole weight: 308.65. | |
TC-S 7009 Quick inquiry Where to buy Suppliers range | TC-S 7009. Group: Biochemicals. Grades: Purified. CAS No. 1422955-31-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |