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| Product | Description | |
|---|---|---|
| LDN 193189 dihydrochloride | LDN 193189 dihydrochloride is a selective ALK2 and ALK3 inhibitor with IC50 values of 5 and 30 nM. It can inhibit FOP and ectopic ossification. LDN 193189 is a potential agent in the treatment of NSCLC lung tumors. Synonyms: LDN 193189 dihydrochloride; LDN193189 dihydrochloride; LDN-193189 dihydrochloride; 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1435934-00-1. Molecular formula: C25H22N6.2HCl. Mole weight: 479.4. |  |
| LDN-193189 dihydrochloride | LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC 50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM-3189 dihydrochloride. CAS No. 1435934-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12071B. |  |
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