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| Product | Description | |
|---|---|---|
| GR 113808 | GR 113808 is a potent and highly selective 5-HT 4 receptor antagonist ( pK b = 8.8). GR 113808 shows 300-fold selectivity over 5-HT 1A , 5-HT 1B , 5-HT 2A , 5-HT 2C and 5-HT 3 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 144625-51-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103152. |  |
| GR 113808 | GR 113808 is a potent and selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, Kd=0.15 nM for binding to cloned human 5-HT4 receptors). GR 113808 displays > 300-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Uses: Serotonin antagonists. Synonyms: GR 113808; GR113808; GR-113808. 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester. Grades: ≥98% by HPLC. CAS No. 144625-51-4. Molecular formula: C19H27N3O4S. Mole weight: 393.5. |  |
| GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808) | A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 144625-51-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. |  Worldwide |
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