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SB 204070 SB 204070 is a potent and selective 5-HT4 receptor antagonist (pIC50 = 10.1), displaying >5000-fold selectivity over 5-HT1A, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2C, and 5-HT3 receptors. SB 204070 exhibits anxiolytic activity upon systemic administration in vivo. Uses: Serotonin antagonists. Synonyms: 1,4-Benzodioxin-5-carboxylic acid, 8-amino-7-chloro-2,3-dihydro-, (1-butyl-4-piperidinyl)methyl ester; (1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-2,3-dihydro-1,4-benzodioxin-5-carboxylate; (1-Butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate; SB204070; SB-204070; (1-Butylpiperidin-4-yl)methyl 8-amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate. Grades: ≥95%. CAS No. 148702-58-3. Molecular formula: C19H27ClN2O4. Mole weight: 382.88. BOC Sciences 10

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