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| Product | Description | |
|---|---|---|
| 15(S)-HpETE | 15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. Synonyms: (S)-15-hpete; 15-Hydroperoxyicosatetraenoate; 15-Hydroperoxyeicosatetraenoate. Grades: ≥98%. CAS No. 70981-96-3. Molecular formula: C20H32O4. Mole weight: 336.5. |  |
| 15(S)-HPETE | 15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A41 or reduced to 15(S)-HETE by peroxidases.2,1 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.3 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO. Uses: Scientific research. Group: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438. |  |
| 15(S)-HPETE | 15(S)-HPETE is a primary metabolite of arachidonic acid shown to inhibit arachidonic acid induced platelet aggregation. Group: Biochemicals. Grades: Highly Purified. CAS No. 70981-96-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. |  Worldwide |
| hydroperoxy icosatetraenoate dehydratase | Binds Fe2+. The mammalian enzymes accept a range of hydroperoxyicosatetraenoates (HPETE). The human enzyme has highest activity with (12R)-HPETE, followed by (12S)-HPETE and (15R)-HPETE with much lower efficiency. The murine enzyme has highest activity with (8R)-HPETE followed by (8S)-HPETE. All HPETE isoforms are converted to the corresponding oxoicosatetraenoate forms (KETE). The enzymes also catalyse the reaction of EC 5.4.4.7, hydroperoxy icosatetraenoate isomerase. Group: Enzymes. Synonyms: epidermal lipoxygenase-3 (ambiguous); eLOX3 (ambiguous). Enzyme Commission Number: EC 4.2.1.152. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4993; hydroperoxy icosatetraenoate dehydratase; EC 4.2.1.152; epidermal lipoxygenase-3 (ambiguous); eLOX3 (ambiguous). Cat No: EXWM-4993. |  |
| Native Glycine max (soybean) Lipoxidase | Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure. Applications: The soybean enzyme will use arachidonic acid as a substrate, with ~ 15% of the activity indicated using linoleic acid as the substrate; the product of arachidonic acid oxidation is 12-or 15-hydroperoxyarachidonic acid (12-hpete or 15-hpete). Group: Enzymes. Synonyms: Lipoxygenases; EC 1.13.11.12; 9029-60-1; 13-lipoxidase; carotene oxidase; 13-lipoperoxidase; fat oxidase; 13-lipoxydase; lionoleate:O2 13-oxidoreductase; linoleate 13S-lipoxygenase. Enzyme Commission Number: EC 1.13.11.12. CAS No. 9029-60-1. Lipoxygenase. Mole weight: mol wt 108 kDa (two 54 kDa subunits). Activity: Type I, 500,000-1,000,000 units/mg protein; Type II, > 50,000 units/mg solid. Storage: 2-8°C. Form: Type I, ammonium sulfate suspension, Suspension in 2.3 M (NH4)2SO4 solution, pH approx. 6.0; Type II, lyophilized powder, Contains stabilizer and NaCl. Source: Glycine max (soybean). Lipoxygenases; EC 1.13.11.12; 9029-60-1; 13-lipoxidase; carotene oxidase; 13-lipoperoxidase; fat oxidase; 13-lipoxydase; lionoleate:O2 13-oxidoreductase; linoleate 13S-lipoxygenase. Cat No: NATE-0407. | |
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