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| Product | Description | |
|---|---|---|
| Oxybutynin chloride | Oxybutynin chloride is an oral active and competitive mAChR antagonist with K i s of 14.3 and 5.55 nM for specific [ 3 H]NMS binding in the mouse bladder and cerebral cortex, respectively. Oxybutynin chloride inhibits vascular Kv channels in a manner independent of anticholinergic effect, with an IC 50 value of 11.51 μM. Oxybutynin chloride reduces muscle spasm in the bladder and urinary tract, can be used in study of overactive bladder syndrome (OAB) [1] [2]. Oxybutynin (chloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1508-65-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0267A. |  |
| Oxybutynin Chloride | An antagonist of muscarinic acetylcholine receptors, anti-spasmodic. An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.Oxybutynin is an antagonist of muscarinic acetylcholine receptors (Kis = 5, 14.5, 3.7, 5.3, and 40nM for human recombinant M1-5, respectively).1 It inhibits intracellular calcium mobilization induced by carbamoylcholine in bladder smooth muscle and submandibular gland cells isolated from cynomolgus monkeys (Kis = 2 and 1nM, respectively).2 Oxybutynin inhibits volume-induced bladder contraction (VIBC) and oxotremorine-induced salivation (OIS) in rats (ID50s = 0.062 and 0.089mg/kg, respectively).1 It also increases pupil diameter (PD) and locomotor activity (LMA; ED50s = 0.29 and 0.52mg/kg, respectively) and decreases small intestinal transit (SIT; ID50 = 0.22mg/kg) in rats. Formulations containing oxybutynin have been used in the treatment of overactive bladder. Group: Biochemicals. Alternative Names: α -Phenylcyclohexane glycol ic acid 4-(diethylamino)-2-butynyl ester hydrochloride; 4-(diethylamino)-2-butyn-1-yl ester α-cyclohexyl-α-hydroxy-benzeneacetic acid, monohydrochloride; MJ4309-1. Grades: Highly Purified. CAS No. 1508-65-2. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C??H??ClNO?, Molecular Weight: 393.95. US Biological Life Sciences. |  Worldwide |
| Oxybutynin HCl | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. Uses: Muscarinic antagonists. Synonyms: Oxybutynin Hydrochloride; Oxybutynin HCl. Grades: >98%. CAS No. 1508-65-2. Molecular formula: C22H31NO3.HCl. Mole weight: 393.95. |  |
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