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| Product | Description | |
|---|---|---|
| TGR-1202 hydrochloride | TGR-1202 hydrochloride is the hydrochloride salt of TGR-1202.TGR-1202, also known as RP5264, is a highly specific, orally available, PI3Kdelta inhibitor which is approximately 1000 -fold selective over alpha isoform, >30-50 fold over beta isoform and >15-. Synonyms: RP5264 hydrochloride; TGR1202 hydrochloride; RP 5264 hydrochloride; TGR 1202 hydrochloride; RP-5264 hydrochloride; TGR-1202 hydrochloride. CAS No. 1532533-78-0. Molecular formula: C31H25ClF3N5O3. Mole weight: 608.01. |  |
| Umbralisib hydrochloride | Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TGR-1202 hydrochloride; RP5264 hydrochloride. CAS No. 1532533-78-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12279C. |  |
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