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| Product | Description | |
|---|---|---|
| Efavirenz | Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a K i of 2.93 nM and exhibits an IC 95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture [1]. Uses: Scientific research. Group: Natural products. Alternative Names: DMP 266; EFV; L-743726. CAS No. 154598-52-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10572. |  |
| Efavirenz (Sustiva, MDP-266, L-743726) | A nonnucleoside HIV-1 reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; DMP 266; L 743726; Stocrin; Sustiva. Grades: Highly Purified. CAS No. 154598-52-4. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C14H9ClF3NO2, Molecular Weight: 315.67. US Biological Life Sciences. |  Worldwide |
| (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one | Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Efavirenz is an NNRTI that prevents RNA plus-strand initiation with an IC50 value of 17 nM. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It has been used in combination therapy with drugs directed at the treatment of opportunistic infections such as HIV and cancer. Synonyms: (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Grades: > 98 %. CAS No. 154598-52-4. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. |  |
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