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TH588 hydrochloride TH588 hydrochloride, with potent anti-cancer property, is a novel inhibitor that highly selectively targets MTH1 protein (IC50= 5 nM) which is required for cancer cell survival and is overexpressed in cancer cells. Synonyms: 4-N-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine;hydrochloride; TH588 (hydrochloride); TH-588 hydrochloride; TH 588 hydrochloride; N4-Cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine hydrochloride; 1640282-30-9. CAS No. 1640282-30-9. Molecular formula: C13H13Cl3N4. Mole weight: 331.63. BOC Sciences 11