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| Product | Description | |
|---|---|---|
| PLX 647 dihydrochloride | PLX 647 is a potent dual KIT/Fms inhibitor (IC50= 16 and 28 nM respectively). PLX 647 blocks activation of macrophages, osteoclasts and mast cells in both cell based and in vivo inflammation models. Synonyms: PLX 647 dihydrochloride; PLX647 dihydrochloride; PLX-647 dihydrochloride; 5-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine dihydrochloride. Grades: ≥97% by HPLC. CAS No. 1779796-38-1. Molecular formula: C21H17F3N4.2HCl. Mole weight: 455.3. |  |
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