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Repotrectinib TPX-0005 is an orally available and potent ATP-competitive inhibitor of ALK/ROS1/TRK (IC50= 5.3 nM for SRC, IC50= 1.01 nM, 1.26 nM and 1.08 nM for mutant ALKs including WT ALK, ALK G1202R and ALK L1196M, respectively). Synonyms: TPX-0005; TPX 0005; TPX0005. CAS No. 1802220-02-5. Molecular formula: C18H18FN5O2. Mole weight: 355.37. BOC Sciences 8