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| Product | Description | |
|---|---|---|
| Tegaserod maleate | Tegaserod maleate. Group: Biochemicals. Grades: Purified. CAS No. 189188-57-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Tegaserod maleate | Tegaserod maleate (SDZ-HTF-919) is an orally active serotonin receptor 4 ( HTR4 ; 5-HT 4 R ) agonist and a 5-HT 2B receptor antagonist. Tegaserod maleate has pK i s of 7.5, 8.4 and 7.0 for human recombinant 5-HT 2A , 5-HT 2B and 5-HT 2C receptors, respectively. Tegaserod maleate causes tumor cell apoptosis , blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod maleate has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-HTF-919; HTF-919. CAS No. 189188-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14153A. |  |
| Tegaserod Maleate | Tegaserod maleate is a partial agonist of the 5-HT4 receptor (Ki = 12 nM) that can treat irritable bowel syndrome (IBS). Uses: A gastroproeinetic used in the treatment of irritable bowel syndrome. a selective serotonin 5ht4-receptor partial agonist. Synonyms: (Z)-but-2-enedioic acid;1-[[(Z)-(5-methoxyindol-3-ylidene)methyl]amino]-2-pentylguanidine5-methoxyindol-3-carboxaldehyde amino(pentylamino)methylenehydrazone hydrogen maleateHTF 919; HTF919; HTF-919SDZ HTF 919SDZ HTF-919tegaserodtegaserod maleateZelmacZelnorm. Grades: ≥99%. CAS No. 189188-57-6. Molecular formula: C20H27N5O5. Mole weight: 417.46. |  |
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