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| Product | Description | |
|---|---|---|
| YKL-05-099 | YKL-05-099 has slightly less potent SIK2-inhibitory (IC50 = 40 ± 25 nM) and IL-10-enhancing activities (EC50 = 460 ± 110 nM), but is non-toxic at concentrations ≤ 10 μM and stable in mouse liver microsomes for > 2 hours. Synonyms: YKL 05 099; YKL05099. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.11. |  |
| YKL-05-099 | YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK). Group: Inhibitors. Alternative Names: YKL-05-099; YKL 05 099; YKL05099. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.12. Appearance: Solid powder. Purity: >98%. IUPACName: 3-(2-Chloro-6-methylphenyl)-7-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-1-(5-methoxypyridin-2-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one. Canonical SMILES: O=C1N (C2=NC=C (OC)C=C2)C3=NC (NC4=CC=C (C5CCN (C)CC5)C=C4OC)=NC=C3CN1C6=C (C)C=CC=C6Cl. Catalog: ACM1936529655. |  |
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