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| Product | Description | |
|---|---|---|
| YKL-05-099 | YKL-05-099 has slightly less potent SIK2-inhibitory (IC50 = 40 ± 25 nM) and IL-10-enhancing activities (EC50 = 460 ± 110 nM), but is non-toxic at concentrations ≤ 10 μM and stable in mouse liver microsomes for > 2 hours. Synonyms: YKL 05 099; YKL05099. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.11. |  |
| YKL-05-099 | YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1936529-65-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-101147. |  |
| YKL-05-099 | YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK). Uses: Designed for use in research and industrial production. Additional or Alternative Names: YKL-05-099; YKL 05 099; YKL05099. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.12. Purity: >98%. IUPACName: 3-(2-Chloro-6-methylphenyl)-7-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-1-(5-methoxypyridin-2-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one. Canonical SMILES: O=C1N(C2=NC=C(OC)C=C2)C3=NC(NC4=CC=C(C5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6Cl. Product ID: ACM1936529655. Alfa Chemistry ISO 9001:2015 Certified. |  |
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