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TNF-α Antagonist TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex, thus preventing ligand interaction with the receptor. Synonyms: W9; H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH (Disulfide bridge: Cys2-Cys8); L-tyrosyl-L-cysteinyl-L-tryptophyl-L-seryl-L-glutaminyl-L-tyrosyl-L-leucyl-L-cysteinyl-L-tyrosine (2->8)-disulfide; WP9QY; N-{[(4R,7S,10S,13S,16S,19S,22R)-13-(3-Amino-3-oxopropyl)-10-(4-hydroxybenzyl)-16-(hydroxymethyl)-19-(1H-indol-3-ylmethyl)-7-isobutyl-6,9,12,15,18,21-hexaoxo-22-(L-tyrosylamino)-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]carbonyl}-L-tyrosine. Grades: ≥95%. CAS No. 199999-60-5. Molecular formula: C58H71N11O15S2. Mole weight: 1226.38. BOC Sciences 9
WP9QY WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.). Uses: Scientific research. Group: Peptides. CAS No. 199999-60-5. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P2612. MedChemExpress MCE

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