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| Product | Description | |
|---|---|---|
| 2'-Amino-2'-deoxyguanosine | 2'-Amino-2'-deoxyguanosine, a modified nucleoside utilized in the development of anticancer drugs, exhibits vast potential in the treatment of a plethora of cancers. By curbing the growth and proliferation of cancer cells, this compound emerges as a promising tool in the fight against cancer. Synonyms: Guanosine, 2'-amino-2'-deoxy-; 9-(2'-Amino-2'-deoxy-β-D-ribofuranosyl)-guanine; 2'-Deoxy-2'-aminoguanosine. Grades: 98%. CAS No. 60966-26-9. Molecular formula: C10H14N6O4. Mole weight: 282.25. |  |
| 2'-Amino-2'-deoxyguanosine | 2'-Amino-2'-deoxyguanosine. Group: Biochemicals. Alternative Names: 9-(2-amino-2-deoxy-b-D-ribofuranosyI)-guanine. Grades: Highly Purified. CAS No. 60966-26-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H14N6O4. US Biological Life Sciences. |  Worldwide |
| 2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt | 2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 2.5mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| 2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt | 2'-Amino-2'-deoxyguanosine-5'-triphosphate tetralithium salt, a compound of utmost importance in the realm of biomedical research and drug discovery, exhibits its significance as a precursor for the synthesis of altered nucleotides, particularly employed in DNA and RNA sequencing. Its indispensable role in elucidating DNA methylation, epigenetic modifications, and mutagenesis studies across diverse ailments, encompassing cancer and genetic disorders, renders it a critical component. Synonyms: 2'-Amino-2'-deoxy-D-guanosine-5'-triphospate tetralithium salt. Grades: 95%. CAS No. 108269-13-2. Molecular formula: C10H17N6O13P3Li4. Mole weight: 549.96. | |
| 2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine | 2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine is an intriguing biomedical agent, conquering the realm of antiviral mastery and enveloping RNA pathogens within its strategic web. Through an artful act of termination, this compound disrupts viral replication. Such fortitude emanates from its prowess in inhibiting viral polymerase activity, thwarting the insidious dance of their replication and gallantly diminishing the burden of viral load. Synonyms: 6-Dma-dguo; 6-Dimethylamino-2'-deoxyguanosine; Adenosine, 2-amino-2'-deoxy-N,N-dimethyl-; 2'-Deoxy-6-dimethylaminoguanosine; 2-Amino-6-(dimethylamino)-9-(2-deoxy-beta-D-ribofuranosyl)-9H-purine; 9-(2-Deoxypentofuranosyl)-2-imino-N,N-dimethyl-2,9-dihydro-1H-purin-6-amine. Grades: ≥95%. CAS No. 83061-20-5. Molecular formula: C12H18N6O3. Mole weight: 294.31. | |
| 2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2 | 2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2, is an intermediate in the synthesis of 8-Oxo-2-deoxyguanosine-13C,15N2 (O850252). A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C1013CH16N415N2O4, Molecular Weight: 299.26. US Biological Life Sciences. | Worldwide |
| 2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine | 2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine, a nucleoside analogue, is a potent antiviral drug utilized by the biomedical industry to combat the insidious Hepatitis B and C viruses. Its mode of action lies in its inhibitory nature, as it halts viral RNA from reverse transcribing into DNA, effectively impeding transmission and replication of the virus. Synonyms: dCpdG; [5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate,azane; DCPDG Ammonium Salt; (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl((2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate,ammonia salt. CAS No. 77710-57-7. Molecular formula: C19H25N8O10P·NH3. Mole weight: 573.45. | |
| 2'NH2-dGTP | 2'NH2-dGTP is a vital biomolecule used in compound serving as a modified nucleotide for DNA research and development, enabling the study and detection of DNA damage and repair. This unique compound finding applications in researching genetic diseases, mutagenesis analysis, and anticancer drug development. Its role in molecular biology facilitates a deeper understanding of nucleotide interactions and contributes to developments in disease reserch. Synonyms: 2'-Amino-2'-deoxyguanosine-5'-triphosphate, Sodium salt; 2'-Amino-dGTP. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N6O13P3 (free acid). Mole weight: 522.20 (free acid). | |
| SGI-110 | SGI-110 is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. Following metabolic activation by phosphorylation and incorporation into DNA, SGI-110 inhibits DNA methyltransferase, thereby causing genome-wide and non-specific hypomethylation and inducing cell cycle arrest at S-phase. This agent is resistant to cytidine deaminase, hence may result in gradual release of decitabine both extra- and intracellularly, leading to more prolonged exposures to decitabine. Uses: Antineoplastic agents. Synonyms: Guadecitabine; SGI 110; SGI110; 2'-deoxy-5-azacytidylyl-(3'->5')-2'-deoxyguanosine; (2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl (((2R,3S,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) hydrogen phosphate. Grades: ≥95%. CAS No. 929901-49-5. Molecular formula: C18H24N9O10P. Mole weight: 557.41. | |
| (1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester | (1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences. | Worldwide |
| 8-(4-Aminophenyl)-2'-deoxyguanosine | 8-(4-Aminophenyl)-2'-deoxyguanosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine | 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine, renowned for its unparalleled efficacy, stands as an indispensable entity within the illustrious biomedical realm. Revered for its unrivaled specificity, this miraculous compound has revolutionized the field by combatting DNA viruses with remarkable prowess. Its potency is particularly evident in its success against the notorious herpes simplex virus (HSV) and hepatitis B virus (HBV). Grades: ≥ 97%. CAS No. 204582-53-6. Molecular formula: C34H35BrN6O6. Mole weight: 703.59. | |
| γ-(6-Aminohexyl)-dGTP | γ-(6-Aminohexyl)-dGTP is an indispensable compound in the field of biomedical sciences, thrives as a fundamental resource for enzymatic DNA labels, DNA sequencing and DNA synthesis endeavors. Its significance transcends boundaries as it actively contributes to advancements in studies pertaining to DNA polymerase and DNA-protein interactions. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C16H29N6O13P3(free acid). Mole weight: 606.36 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - ATTO-488 | γ-(6-Aminohexyl)-dGTP - ATTO-488 is a fluorescently labeled nucleotide analog widely used in biomedical research. It serves as a powerful tool for studying DNA synthesis and repair mechanisms. This product is essential for labeling specific DNA sequences and monitoring their interactions with proteins or enzymes involved in DNA replication, transcription and translation. Its compatibility with various imaging techniques makes it ideal for visualizing DNA dynamics in live cells and tissues. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO-488, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C41H49N9O22P3S2(free acid). Mole weight: 1176.93 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - ATTO-532 | γ-(6-Aminohexyl)-dGTP - ATTO-532, a sensational fluorescent nucleotide analogue, can be effectively used for observing and examining DNA replication and repair processes. With the inclusion of this compound in the DNA synthesis process, one can dynamically track the progression of DNA replication and repair events via fluorescence microscopy, making it ideal for research and diagnostic purposes. Not only that, but it also plays a crucial role in detecting genetic mutations and polymorphisms and can be used in DNA sequencing techniques. This product holds a critical place in both diagnostic and research communities, particularly in investigating genetic diseases and cancer. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO-532, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C45H57N9O22P3S2(free acid). Mole weight: 1233.03 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - ATTO-540Q | γ-(6-Aminohexyl)-dGTP - ATTO-540Q is a versatile fluorescent nucleotide analog empowering with groundbreaking applications, including nucleic acid sequencing, genotyping and DNA labeling, the remarkable ATTO-540Q dye effortlessly illuminates and unravels the mysteries of genetic analysis, diagnostics and drug discovery. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO 540Q, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H29N6O13P3- ATTO 540Q (free acid). Mole weight: 1147.5 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - ATTO-647N | γ-(6-Aminohexyl)-dGTP - ATTO-647N is an indispensable compound, revered for its exceptional aptitude in conferring definitive identification to DNA sequences. Its intrinsic peculiarity lies in the capacity to effectively and discernibly label nucleotides alongside DNA synthesis. Embracing distinctive fluorescent characteristics, it remarkably facilitates the visual tracking of DNA during an extensive gamut of applications, such as PCR, sequencing and fluorescence in situ hybridization. This paramount product assumes a cardinal role in delving into genetic diseases, DNA-protein interactions and gene expression analysis. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO-647N, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C16H29N6O13P3- ATTO 647N (free acid). Mole weight: 1233.36 (free acid). | |
| γ-(6-Aminohexyl)-dGTP-ATTO-MB2 | γ-(6-Aminohexyl)-dGTP-ATTO-MB2, a fluorescent nucleotide probe, finds utility in biomedical research for DNA detection and sequencing. This probe flawlessly incorporates into a DNA template during PCR enabling detection of mutations in all genomic regions. With the ability to specifically detect drug-resistant mutations, it has vast applications in diseases such as cancer, including real-time PCR, and DNA sequencing. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate-ATTO-MB2. Grades: ≥ 95 % by HPLC. Molecular formula: C35H48N9O14P3S (free acid). Mole weight: 943.79 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - ATTO-Rho6G | γ-(6-Aminohexyl)-dGTP - ATTO-Rho6G, a fluorescently labeled nucleotide frequently employed in the applications of DNA sequencing and PCR, possesses high sensitivity and can detect DNA even in tiny quantities. With its versatile single molecule analysis capabilities, this labeling reagent has emerged as a valuable tool in advancing studies of DNA repair and replication. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with ATTO Rho6G, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C47H62N9O16P3(free acid). Mole weight: 1101.35 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - Cy3 | γ-(6-Aminohexyl)-dGTP - Cy3, a fluorescent nucleotide, is an essential innovation in the field of biomedical exploration, catering to diverse applications like precise DNA identification, sequencing, and monitoring. The incorporation of a Cy3 fluorophore lavishly exhibits the intricate and enigmatic dynamics involved in DNA replication and rectification. Such superior functionalities of this compound can be further utilized in effective gene-expression examination and detailed DNA-protein interaction analysis, thereby adding a new dimension to scientific discovery. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C47H65N8O20P3S2(free acid). Mole weight: 1219.11 (free acid). | |
| γ-(6-Aminohexyl)-dGTP - Cy5 | γ-(6-Aminohexyl)-dGTP - Cy5, a fluorescent nucleotide analog utilized for in vitro transcriptional and translational investigations, boasts an extensive range of applications. High in demand for DNA sequencing, genetic analysis, and real-time PCR assays, this product provides an indispensable tool to detect mutations and gene expression. Its criticality in medical research involving cancer, viral infections, and neurological disorders makes it a breakthrough discovery in the scientific community. Synonyms: γ-(6-Aminohexyl)-2'-deoxyguanosine-5'-triphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C49H67N8O20P3S2(free acid). Mole weight: 1245.15 (free acid). | |
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