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2'-Amino-2'-deoxyguanosine, a modified nucleoside utilized in the development of anticancer drugs, exhibits vast potential in the treatment of a plethora of cancers. By curbing the growth and proliferation of cancer cells, this compound emerges as a promising tool in the fight against cancer. Synonyms: Guanosine, 2'-amino-2'-deoxy-; 9-(2'-Amino-2'-deoxy-β-D-ribofuranosyl)-guanine; 2'-Deoxy-2'-aminoguanosine. Grade: 98%. CAS No. 60966-26-9. Molecular formula: C10H14N6O4. Mole weight: 282.25.
2'-Amino-2'-deoxyguanosine
2'-Amino-2'-deoxyguanosine. Group: Biochemicals. Alternative Names: 9-(2-amino-2-deoxy-b-D-ribofuranosyI)-guanine. Grades: Highly Purified. CAS No. 60966-26-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H14N6O4. US Biological Life Sciences.
Worldwide
2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt
2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 2.5mg, 5mg, 10mg. US Biological Life Sciences.
Worldwide
2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt
2'-Amino-2'-deoxyguanosine-5'-triphosphate tetralithium salt, a compound of utmost importance in the realm of biomedical research and drug discovery, exhibits its significance as a precursor for the synthesis of altered nucleotides, particularly employed in DNA and RNA sequencing. Its indispensable role in elucidating DNA methylation, epigenetic modifications, and mutagenesis studies across diverse ailments, encompassing cancer and genetic disorders, renders it a critical component. Synonyms: 2'-Amino-2'-deoxy-D-guanosine-5'-triphospate tetralithium salt. Grade: 95%. CAS No. 108269-13-2. Molecular formula: C10H17N6O13P3Li4. Mole weight: 549.96.
2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine
2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine is an intriguing biomedical agent, conquering the realm of antiviral mastery and enveloping RNA pathogens within its strategic web. Through an artful act of termination, this compound disrupts viral replication. Such fortitude emanates from its prowess in inhibiting viral polymerase activity, thwarting the insidious dance of their replication and gallantly diminishing the burden of viral load. Synonyms: 6-Dma-dguo; 6-Dimethylamino-2'-deoxyguanosine; Adenosine, 2-amino-2'-deoxy-N,N-dimethyl-; 2'-Deoxy-6-dimethylaminoguanosine; 2-Amino-6-(dimethylamino)-9-(2-deoxy-beta-D-ribofuranosyl)-9H-purine; 9-(2-Deoxypentofuranosyl)-2-imino-N,N-dimethyl-2,9-dihydro-1H-purin-6-amine. Grade: ≥95%. CAS No. 83061-20-5. Molecular formula: C12H18N6O3. Mole weight: 294.31.
2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2
2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2, is an intermediate in the synthesis of 8-Oxo-2'-deoxyguanosine-13C,15N2. A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. It can induce differentiation of Friend murine erythroleukemia cells in vitro. Synonyms: 2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2; 2-Amino-N6-methoxy-2'-deoxyadenosine-13C,15N2; DK-13C,15N2; K-2'-Deoxyribose-13C,15N2; K-Nucleoside (dK)-13C,15N2. Molecular formula: C10[13C]H16N4[15N]2O4. Mole weight: 299.26.
2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2
2-Amino-2'-deoxy-N-methoxyadenosine-13C,15N2, is an intermediate in the synthesis of 8-Oxo-2-deoxyguanosine-13C,15N2 (O850252). A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C1013CH16N415N2O4, Molecular Weight: 299.26. US Biological Life Sciences.
Worldwide
2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine
2'-Deoxycytidyl-(3'-5')-2'-deoxyguanosine, a nucleoside analogue, is a potent antiviral drug utilized by the biomedical industry to combat the insidious Hepatitis B and C viruses. Its mode of action lies in its inhibitory nature, as it halts viral RNA from reverse transcribing into DNA, effectively impeding transmission and replication of the virus. Synonyms: dCpdG; [5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate,azane; DCPDG Ammonium Salt; (2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl((2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate,ammonia salt. CAS No. 77710-57-7. Molecular formula: C19H25N8O10P·NH3. Mole weight: 573.45.
2'NH2-dGTP
2'NH2-dGTP is a vital biomolecule used in compound serving as a modified nucleotide for DNA research and development, enabling the study and detection of DNA damage and repair. This unique compound finding applications in researching genetic diseases, mutagenesis analysis, and anticancer drug development. Its role in molecular biology facilitates a deeper understanding of nucleotide interactions and contributes to developments in disease reserch. Synonyms: 2'-Amino-2'-deoxyguanosine-5'-triphosphate, Sodium salt; 2'-Amino-dGTP. Grade: ≥ 95% by HPLC. Molecular formula: C10H17N6O13P3 (free acid). Mole weight: 522.20 (free acid).
(1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences.
Worldwide
8-(4-Aminophenyl)-2'-deoxyguanosine
8-(4-Aminophenyl)-2'-deoxyguanosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.
8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine, renowned for its unparalleled efficacy, stands as an indispensable entity within the illustrious biomedical realm. Revered for its unrivaled specificity, this miraculous compound has revolutionized the field by combatting DNA viruses with remarkable prowess. Its potency is particularly evident in its success against the notorious herpes simplex virus (HSV) and hepatitis B virus (HBV). Grade: ≥ 97%. CAS No. 204582-53-6. Molecular formula: C34H35BrN6O6. Mole weight: 703.59.
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