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| Product | Description | |
|---|---|---|
| 2'-Bromo-2'-deoxyuridine | 2'-Bromo-2'-deoxyuridine. Group: Biochemicals. Alternative Names: 2'-Bromo-D-uridine. Grades: Highly Purified. CAS No. 4753-02-0,72218-68-9. Pack Sizes: 100mg, 200mg, 500mg, 1g, 2g. Molecular Formula: C9H11BrN2O5. US Biological Life Sciences. |  Worldwide |
| 2'-Bromo-2'-deoxyuridine | 2'-Bromo-2'-deoxyuridine is a chemical compound commonly used in biomedical research. It acts as a thymidine analog, incorporating into DNA during replication and inhibiting cell proliferation. This compound is particularly useful in studying DNA synthesis, cell cycle progression, and mutagenesis. It is also utilized in the research of viral infections and certain cancers due to its antiviral and antineoplastic properties. Synonyms: 2'-Bromo-2'-deoxy-D-uridine; 1-((2R,3R,4R,5R)-3-bromo-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Bromo-2-deoxy-beta-D-xylofuranosyl)uracil; 1-(2-Bromo-2-deoxypentofuranosyl)-4-hydroxypyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 4753-02-0. Molecular formula: C9H11BrN2O5. Mole weight: 307.10. |  |
| 2'-Bromo-2'-deoxyuridine-[82Br] | 2'-Bromo-2'-deoxyuridine-[82Br]. Synonyms: 2'-Bromo-2'-deoxyuridine-82Br; Uridine, 2'-(bromo-82Br)-2'-deoxy-; 2'-(82Br)Bromo-2'-deoxyuridine. Grade: 95%. CAS No. 72218-68-9. Molecular formula: C9H11[82Br]N2O5. Mole weight: 309.11. | |
| 2-Bromo-2-deoxyuridine | 2-Bromo-2-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2'-Bromo-2'-deoxy-D-uridine. CAS No. 4753-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W141338. |  |
| 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine | An intermediate in the preparation of cytidine derivatives. Group: Biochemicals. Alternative Names: 5-Bromo-2'-deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-uridine. Grades: Highly Purified. CAS No. 154925-95-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine | 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 6161-23-5. Pack Sizes: 1g, 2g, 5g. Molecular Formula: C13H15BrN2O7. US Biological Life Sciences. | Worldwide |
| 5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt | 5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt. Group: Biochemicals. Alternative Names: 5-BrdUMP. 2Na. Grades: Highly Purified. CAS No. 51432-32-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H12BrN2O8PNa2. US Biological Life Sciences. | Worldwide |
| 5-Bromo-2'-deoxyuridine 99+% (HPLC) | 5-Bromo-2'-deoxyuridine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| 5-O-(4,4-Dimethoxytrityl)-5-bromo-2-deoxyuridine | 5-O-(4,4-Dimethoxytrityl)-5-bromo-2-deoxyuridine. Group: Biochemicals. Alternative Names: 5'-O-[Bis (4-methoxyphenyl) phenylmethyl]-5-bromo-2'-deoxyuridine. Grades: Highly Purified. CAS No. 63660-21-9. Pack Sizes: 1g. Molecular Formula: C30H29BrN2O7, Molecular Weight: 609.46. US Biological Life Sciences. | Worldwide |
| 2'-Bromo-2'-deoxy-3'-O-methanesulfonyluridine | 2'-Bromo-2'-deoxy-3'-O-methanesulfonyluridine is a remarkable antiviral compound employed in the research of diverse viral afflictions, encompassing herpes simplex and Epstein-Barr virus infections. It exhibits its efficacy by thwarting viral replication via its assimilation into viral DNA and consequential cessation of DNA chain elongation. Synonyms: 5-Bromo-2'-deoxyuridine 5'-triphosphate sodium salt; Brdutp; 102212-99-7; [[(2R,3S,5R)-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Bromodeoxyuridine triphosphate; Uridine5'-(tetrahydrogen triphosphate), 5-bromo-2'-deoxy-, tetrasodium salt (9CI); 5-Bromodeoxyuridine triphosphate; 5-BrdUTP; 5-bromo-2'-deoxyuridine 5'-triphosphate; SCHEMBL150029; DTXSID30940203; MFCD00057405; PD148794; J-000655; Uridine 5'-(tetrahydrogen triphosphate), 5-bromo-2'-deoxy-; ((2R,3S,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5-Bromo-1-[2-deoxy-5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)pentofuranosyl]-4-hydroxypyrimidin-2(1H)-one. CAS No. 18736-53-3. Molecular formula: C9H14BrN2O14P3. Mole weight: 547.04. | |
| 2'-Bromo-2'-deoxy-5-fluorouridine | 2'-Bromo-2'-deoxy-5-fluorouridine is a nucleoside analog that interferes with RNA and DNA synthesis, used as an antineoplastic agent against certain types of cancer including pancreatic, colorectal and breast cancer. It can also be used clinically as a prodrug, in combination with other anticancer agents, to increase their efficacy. Synonyms: Uridine, 2'-bromo-2'-deoxy-5-fluoro-; 5-Fluor-2'-brom-2'-deoxyuridine; 1-((2R,3R,4R,5R)-3-Bromo-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-1H-pyrimidine-2,4-dione; 1-[(2R,3R,4R,5R)-3-bromo-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grade: ≥95%. CAS No. 32791-82-5. Molecular formula: C9H10BrFN2O5. Mole weight: 325.09. | |
| 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine | 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a potent antiviral compound widely used in biomedical research. It has demonstrated efficacy against various viruses, including influenza and herpes simplex viruses. This compound inhibits viral replication by interfering with the viral DNA/RNA synthesis process. Its unique chemical structure makes it a valuable tool in studying viral pathogenesis and designing targeted therapeutic strategies. Synonyms: 5-Bromo-2'-deoxy-2'-fluoro-3',5'-di-O-acetyluridine; 5-bromo-3',5'-diacetyl-2'-fluoro-2'-deoxyuridine; ((2R,3R,4R,5R)-3-acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl acetate; 5-Bromo-2'-deoxy-2'-fluorouridine 3',5'-diacetate. Grade: ≥95%. CAS No. 1188522-91-9. Molecular formula: C13H14BrFN2O7. Mole weight: 409.16. | |
| 3',5'-Di-O-acetyl-5-bromo-2'-Deoxy-d-uridine | 3',5'-Di-O-acetyl-5-bromo-2'-Deoxy-d-uridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3, 5-Di-O-acetyl-5-bromo-2-deoxyuridine, CTK8F4759, 6161-23-5, ZINC22056595, AG-G-24686, 3,5-DI-O-ACETYL-5-BROMO-2-DEOXY-D-URIDINE. Product Category: Heterocyclic Organic Compound. CAS No. 6161-23-5. Molecular formula: C13H15BrN2O7. Mole weight: 391.172. Purity: 0.96. IUPACName: [(2R,3R,5R)-3-acetyloxy-5-(5-bromo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate. Canonical SMILES: CC(=O)OCC1C(CC(O1)N2C=C(C(=O)NC2=O)Br)OC(=O)C. Density: 1.667g/cm³. Product ID: ACM6161235. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 5-Br-dU-CE Phosphoramidite | 5-Br-dU-CE Phosphoramidite, a chemical compound used in oligonucleotide synthesis, boasts a 5-bromo-2'-deoxyuridine (Br-dU) group that is linked to a cytosine base, thereby elevating base-pairing specificity and amplifying nuclease resistance. Its potential applications in the realm of biomedical research, encompassing cancer treatment, antiviral agents, and gene therapy, warrant close scrutiny. Synonyms: 5'-Dimethoxytrityl-5-bromo-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C39H46BrN4O8P. Mole weight: 809.69. | |
| 5-Br-dU-CPG | 5-Br-dU-CPG, a chemical highly relevant to the biomedicine industry, offers paradigm-shifting possibilities with regards to the development of nucleic acid derivatives utilized in the treatment of cancer, viral infections, and genetic disorders. As a potent inhibitor for nucleic acid synthesis, 5-Br-dU-CPG paves the way for an epochal suppression of tumor cell proliferation. Evidencing its versatility, this chemical also displays antiviral activity against herpes simplex virus-1, emphasizing its potential in treating viral infections as well. Synonyms: 5'-Dimethoxytrityl-5-bromo-2'-deoxyUridine, 2'-succinoyl-long chain alkylamino-CPG. | |
| 5-Bromo-2',3'-dideoxyuridine | 5-Bromo-2',3'-dideoxyuridine stands as an exemplary nucleoside analog, exhibiting remarkable antiviral prowess. Revered for its potential in combating viral infections instigated by herpesviruses, most notably herpes simplex and varicella-zoster viruses, this therapeutic agent actively hampers viral DNA polymerase, safeguarding against replication and dispersal. This distinctive mode of operation positions it as a formidable contender within the realm of antiviral therapy. Synonyms: Uridine, 5-bromo-2',3'-dideoxy-; 5-Br-ddU; 5-bromodeoxy-2'-deoxyuridine; 5-bromo-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. CAS No. 28616-93-5. Molecular formula: C9H11BrN2O4. Mole weight: 291.1. | |
| 5-Bromo-2'-deoxy-2',2'-difluorouridine | 5-Bromo-2'-deoxy-2',2'-difluorouridine is an intermediate in synthesizing 5'O,6-Cyclo-dihydro-2',2'-difluoro-2'-deoxyuridine, which is an impurity (a product of degradation) of Gemcitabine, an antineoplastic agent. Synonyms: 5-Bromo-2'-deoxy-2',2'-difluorouridine. CAS No. 132786-35-7. Molecular formula: C9H9BrF2N2O5. Mole weight: 343.08. | |
| 5-Bromo-2'-deoxy-2',2'-difluorouridine 5'-O-Acetate | 5-Bromo-2'-deoxy-2',2'-difluorouridine 5'-O-Acetate is an intermediate in synthesizing 5'O,6-Cyclo-dihydro-2',2'-difluoro-2'-deoxyuridine, which is an impurity (a product of degradation) of Gemcitabine Hydrochloride which is an antineoplastic agent. Synonyms: ((2R,3R,5R)-5-(5-Bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl Acetate. Molecular formula: C11H11BrF2N2O6. Mole weight: 385.12. | |
| 5-Bromo-2-deoxy-2-fluorouridine | 5-Bromo-2'-deoxy-2'-fluorouridine is an analog of Uridine and used as a reagent in the synthesis of β-D-arabinofuranosyl and deoxyfluoro-β-D-ribofuranosyl pyrimidine nucleoside analogs which exhibit antituberculosis activity against Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium in vitro. Synonyms: 55612-18-5; 5-bromo-1-[(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 5-Bromo-1-(2-fluoro-2-deoxyribofuranosyl)uracil; 5-Bfdu; 5-Bromo-1-(2-fluoro-2-deoxyuridine); 5-Bromo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracil; DTXSID80970954; Uridine, 5-bromo-2'-deoxy-2'-fluoro-; 5-(76Br)bromo-2'-fluoro-2'-deoxyuridine; 5-Bromo-1-(2-deoxy-2-fluoropentofuranosyl)-4-hydroxypyrimidin-2(1H)-one; 5-bromo-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 55612-18-5. Molecular formula: C29H21NO4. Mole weight: 447.5. | |
| 5-Bromo-2'-deoxy-5'-O-DMT-uridine | 5-Bromo-2'-deoxy-5'-O-DMT-uridine is a highly esteemed compound, exerting profound pharmacological potency in research of an assorted array of ailments, encompassing malignant neoplasms, viral affections and hereditary anomalies. The distinctive configuration of its chemical constitution endows it with the capability to diligently zero in on designated intracellular routes, substantially impeding the development of maladies whilst fostering the proliferation of salubrious cells. Synonyms: 5-Bromo-2'-deoxy-5'-O-DMT-D-uridine; 5-Bromo-5'-O-DMT-2'-deoxyuridine. Grade: 98%. Molecular formula: C30H29BrN2O7. Mole weight: 609.48. | |
| Bromodeoxyuridine (BrdU) | 5-Bromo-2'-deoxyuridine (5-BrdU) is a thymidine analog that can be incorporated into newly synthesized DNA to label it. Synonyms: 5-Bromo-2'-deoxyuridine; BrdU; Bromodeoxyuridine; Broxuridine; NSC 38297; 5-Bromo-1-(2-deoxy-beta-D-ribofuranosyl)uracil; 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione; 5-Bromodeoxyuridine. Grade: ≥98% by HPLC. CAS No. 59-14-3. Molecular formula: C9H11BrN2O5. Mole weight: 307.10. | |
| Bromodeoxyuridine (BrdU) | 5-Bromo-2-deoxyuridine (BrdU) is an analog of thymidine, and can be incorporated into the newly synthesized DNA of replicating cells (S-phase cells). BrdU is a commonly used in the detection of proliferating cells in living tissues. It works by substituting for thymidine during DNA replication and incorporating itself into the newly synthesized DNA (during S-phase). Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Because BrdU can replace thymidine during the S phase of cell division, it can cause mutations. Bromodeoxyuridine (BrdU) is also used to prepare dNTP-BrdU solution for UV cross-linking of proteins to nucleic acids and to prepare complete MEM-10-Brdu or MEM-20-Brdu for vaccinia virus stock cultures. Group: Biochemicals. Alternative Names: 5-Bromo-2-deoxyuridine; 5-BrdU; 2-Deoxy-5-bromorouridine; (+)-5-Bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; Bromodeoxyuridine; Broxuridine; NSC 38297. Grades: Molecular Biology Grade. CAS No. 59-14-3. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C9H11BrN2O5, Molecular Weight: 307.1. US Biological Life Sciences. | Worldwide |
| 5-(E)-(2-Bromovinyl)-2'-deoxyuridine | 5-(E)-(2-Bromovinyl)-2'-deoxyuridine. Group: Biochemicals. Alternative Names: Brivudine. Grades: Highly Purified. CAS No. 69304-47-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C11H13BrN2O5. US Biological Life Sciences. | Worldwide |
| Brivudine | Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator of transcription 3), which may result in the downregulation of vascular endothelial growth factor (VEGF). BVDU has also been found to inhibit the upregulation of chemoresistance genes (Mdr1 and DHFR) during chemotherapy. Overall, the gene expression changes associated with BVDU treatment result in the decrease or prevention of chemoresistance. In addition, this agent has been shown to enhance the cytolytic activity of NK-92 natural killer cells towards a pancreatic cancer cell line in vitro. Synonyms: (E)-5-(2-Bromovinyl)-2'-deoxyuridine; (E)-5-(2-Bromovinyl)deoxyuridine; (E)-5-O-(2-bromoethenyl)-2'-deoxyuridine; 5-[(1E)-2-Bromoethenyl]-2'-deoxyuridine; 5-[(E)-2-Bromoethenyl]-2'-deoxyuridine; BVDU; Brivudin; Bromovinyldeoxyuridine; Helpin. Grade: ≥98% by HPLC. CAS No. 69304-47-8. Molecular formula: C11H13BrN2O5. Mole weight: 333.14. | |
| Brivudine 5'-Monophosphate | Brivudine 5'-Monophosphate is a hetero-dinucleotide that acts as an anti-tumor agent against AH13 rat sarcoma cells. A nucleotide derivative which is an active species of the novel anticancer drug, NB 1011. Anti-viral. Synonyms: BVDU 5'-Monophosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine 5'-Monophosphate; 5-[(1E)-2-Bromoethenyl]-2'-deoxy-5'-uridylic Acid; (E)-5-(2-bromoethenyl)-2'-deoxy-5'-uridylic Acid. CAS No. 80860-82-8. Molecular formula: C11H14BrN2O8P. Mole weight: 413.12. | |
| Brivudine 5'-Triphosphate Ammonium | Brivudine 5'-Triphosphate Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-herpes medication. Synonyms: 5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-(2-bromoethenyl)-2'-deoxy-, (E)-; BVdUTP; BV(5)Dutp; Bvdu-tp; SCHEMBL442341; SCHEMBL442343; CHEMBL4594370; (E)-5-(2-Bromovinyl)-dUTP; Brivudine 5'-Triphosphate Ammonium; E-5-Bromovinyl-2'-deoxyuridine triphosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine triphosphate; (e)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-2-bromoethenyl]-2'-deoxy-; ((2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromovinyl]-2,4-dioxo-pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate. Molecular formula: C11H16BrN2O14P3. Mole weight: 573.08. | |
| (E)-5-(2-Bromovinyl)-2'-deoxyuridine 99+% | (E)-5-(2-Bromovinyl)-2'-deoxyuridine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
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