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2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1 O 2 , the guanine base of 2'-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 312693-72-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-D0185.
2'-Deoxyguanosine monohydrate (dG)
2'-Deoxyguanosine Monohydrate (dG) is a preeminent substrate widely employed in investigating and edifying the pharmacological aspects of antiviral compounds. Deemed indispensable in anti-DNA viral reserch, this quintessential compound demonstrates pivotal efficacy when battling a plethora of DNA-related viruses, notably varicella-zoster, herpes simplex, and cytomegalovirus. Notable employment of 2'-Deoxyguanosine Monohydrate encompasses its irreplaceability in viral DNA quantification and detection within diverse diagnostic assays. Synonyms: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)guanine Monohydrate; Deoxyguanosine Monohydrate; Guanine Deoxyriboside Monohydrate; NSC 22837; 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one hydrate. Grades: ≥99% by HPLC. CAS No. 312693-72-4. Molecular formula: C10H13N5O4.H2O. Mole weight: 285.26.
2'-Deoxyguanosine-1-13C Monohydrate
Isotope labelled analogue of 2-Deoxyguanosine, a nucleoside analog. Group: Biochemicals. Alternative Names: 9-(2-Deoxy- β-D-erythro-pentofuranosyl)guanine-1-13C Monohydrate; Deoxyguanosine-1-13C Monohydrate; Guanine Deoxyriboside-1-13C Monohydrate; NSC 22837-1-13C. Grades: Highly Purified. CAS No. 478511-26-1. Pack Sizes: 250ug. Molecular Formula: C913CH15N5O5, Molecular Weight: 285.24. US Biological Life Sciences.
1g Pack Size. Group: Biochemicals, Building Blocks. Formula: C10H13N5O4 · H2O. CAS No. 961-07-9. Prepack ID 15163303-1g. Molecular Weight 285.26. See USA prepack pricing.
2'-Deoxyguanosine, Monohydrate
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides. Group: Biochemicals. Alternative Names: 2-Deoxyguanosine monohydrate; Guanine 2-deoxyribonucleoside; 9-(2-Deoxy-b-D-erythro-pentofuranosyl)guanine monohydrate; NSC 22837. Grades: Molecular Biology Grade. CAS No. 961-07-9, 312693-72-4. Pack Sizes: 1g, 10g, 25g. Molecular Formula: C10H13N5O4 H2O, Molecular Weight: 285.26. US Biological Life Sciences.
2-Deoxyguanosine 3'-Monophosphate 5'-Triphosphate Triethylamine Salt
Deoxyguanosine 3'-Monophosphate 5'-Triphosphate is a derivative of 2-Deoxyguanosine (D239550, Monohydrate) which is a nucleoside analog. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C10H17N5O16P4; xC6H15N, Molecular Weight: 587.161011899999. US Biological Life Sciences.
Worldwide
2'-Deoxyguanosine hydrate
2'-Deoxyguanosine hydrate, a profoundly significant compound within the biomedical realm, showcases remarkable therapeutic attributes. Primarily recognized for its indispensable role as a fundamental constituent in DNA synthesis and repair, this compound has displayed remarkable efficacy in combating viral infections, malignancies, and select autoimmune disorders. Synonyms: 2'-Deoxyguanosine monohydrate. Grades: 98%. CAS No. 207121-55-9. Molecular formula: C10H13N5O4.xH2O. Mole weight: 267.25 (anhydrous).
2'-Deoxycytidine hydrochloride
2'-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. Synonyms: 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251; NSC83251; NSC-83251. Grades: ≥ 97%. CAS No. 3992-42-5. Molecular formula: C9H13N3O4¡¤ HC. Mole weight: 263.68.
CI 972
This active molecular is a potent purine nucleoside phosphorylase inhibitor and a T cell-selective immunosuppressive agent. CI-972 inhibited proliferation of human MOLT-4 (T cell) and not MGL-8 (B cell) lymphoblasts with respective IC50s of 3.0 and greater than 50 microM when tested with 10 microM 2'-deoxyguanosine. In Apr 1996, Immunological Disorders section added to drug profile and Immunological disorders in USA was discontinued. Uses: Immunological disorders; transplant rejection. Synonyms: CI 972; CI972; CI-972. 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 2,6-diamino-1,5-dihydro-7-(3-thienylmethyl)-, monohydrochloride. Grades: 98%. CAS No. 115787-68-3. Molecular formula: C11H12ClN5OS. Mole weight: 297.76.
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