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2'-O- (2-Methoxyethyl) guanosine. Group: Biochemicals. Alternative Names: 2'-O-MOE-Guanosine. Grades: Highly Purified. CAS No. 473278-54-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C13H19N5O6. US Biological Life Sciences.
Worldwide
2'-O-(2-Methoxyethyl)guanosine
It is a guanosine derivative as a building block for crosslinking oligonucleotides. Synonyms: Guanosine, 2'-O-(2-methoxyethyl)-; 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one; 2'-MOE-rG; 2'-O-Methoxyethyl-guanosine; 2'-O-MOE-rG. Grade: ≥95%. CAS No. 473278-54-5. Molecular formula: C13H19N5O6. Mole weight: 341.32.
2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate
2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate, a profound compound extensively employed in biomedicine, stands as an indispensable weapon against viral afflictions. Notably, this antiviral agent effectively thwarts the proliferation of diverse viral strains, demonstrating its immense potential for therapeutic intervention. Moreover, owing to its distinctive attributes, this compound holds great promise in combating maladies arising from highly specific viral strains, thereby paving the way for groundbreaking advancements in the realm of antiviral investigation and pharmaceutical innovation. Synonyms: 2'-O-(2-methoxyethyl)guanosine 5'-(dihydrogen phosphate). Molecular formula: C13H20N5O9P. Mole weight: 421.3.
2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium salt
2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium salt is a vital recompound in research, allowing the modification of mRNA during the research and development of therapeutic proteins. This compound is instrumental in the development of innovative drugs targeting various diseases such as cancer, genetic disorders, and viral infections. Synonyms: (((2R,3R,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3-hydroxy-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)methyl)triphosphoric ammonium salt. Molecular formula: C13H34N9O15P3. Mole weight: 649.38.
3'-O-(2-Methoxyethyl)guanosine
3'-O-(2-Methoxyethyl)guanosine is a remarkable modified nucleoside with immense potential in the field of antiviral drug discovery. This exquisite compound takes center stage in targeting viral RNA-dependent RNA polymerases, thus rendering it a powerful weapon in research of respiratory syncytial virus (RSV) and hepatitis C virus (HCV). Synonyms: Guanosine, 3'-O-(2-methoxyethyl)-; 3'-O-MOE-G; 2-Amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one. Grade: ≥95%. CAS No. 256224-03-0. Molecular formula: C13H19N5O6. Mole weight: 341.32.
3'-O-(4,4-Dimethoxytrityl)-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is a remarkable compound, exhibiting profound utility in research of combating RNA-based maladies. Grade: ≥95%. Molecular formula: C38H43N5O9. Mole weight: 713.78.
5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine, an intriguing bioactive compound, has garnered attention in the biomedical industry for its potential antiviral prowess. Demonstrating commendable efficacy in impeding viral replication, it holds promise in combatting viral ailments such as herpes and hepatitis. However, the precise workings of this compound remain enigmatic, warranting further exploration in the realm of antiviral drug development. Synonyms: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-O-MOE-5'-O-DMT-G(iBu); 5'-O-DMT-2'-O-MOE-N2-iBu-rG; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine. Grade: ≥95%. CAS No. 251647-50-4. Molecular formula: C38H43N5O9. Mole weight: 713.78.
5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt
5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt, a highly potent compound, is extensively employed in the biomedical arena for multifarious ailment therapies. It demonstrates remarkable therapeutic possibilities by precisely targeting intricate genetic pathways implicated in malignant neoplasms and viral infestations. Notably, its exceptional selectivity and efficacy impede cancer cell proliferation and regulate viral replication, propelling its eminence as a propitious contender for progressive drug advancement and meticulous scientific investigation. Molecular formula: C49H52N5O13·C6H16N. Mole weight: 1021.16.
5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O-(2-methoxyethyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-(2-methoxyethyl)guanosine. Grade: ≥95%. CAS No. 251647-55-9. Molecular formula: C47H60N7O10P. Mole weight: 913.99.
Frenlosirsen
Frenlosirsen is an interferon regulatory factor 4 (IRF4) synthesis reducer, with antineoplastic properties. Synonyms: all-P-ambo-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-P-thioadenylyl-(3'→5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-P-thioguanylyl-(3'→5')-P-thiothymidylyl-(3'→5')-P-thiothymidylyl-(3'→5')-2'-deoxy-P-thioguanylyl-(3'→5')-P-thiothymidylyl-(3'→5')-2'-deoxy-P-thioadenylyl-(3'→5')-2'-deoxy-P-thioadenylyl-(3'→5')-2'-deoxy-P-thioadenylyl-(3'→5')-P-thiothymidylyl-(3'→5')-2'-deoxy-P-thioguanylyl-(3'→5')-2'-O-(2-methoxyethyl)-P-thioadenylyl-(3'→5')-2'-O-(2-methoxyethyl)-P-thioguanylyl-(3'→5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiouridylyl-(3'→5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiocytidylyl-(3'→5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]guanosine; DNA, d(P-thio)((2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)A-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)G-T-T-G-T-A-A-A-T-G-(2'-O-(2-methoxyethyl))rA-(2'-O-(2-methoxyethyl))rG-(2'-O-(2-methoxyethyl))m5rU-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)m5C-(3'->4')-(2',5'-anhydro-6'-deoxy-4'-C-(hydroxymethyl)-alpha-L-mannofurano)G). CAS No. 2304711-81-5. Molecular formula: C177H226N63O89P15S15. Mole weight: 5605.71.
Guanosine, 3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl), 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a chemical utilized in RNA synthesis. It serves as a modified nucleoside to improve the binding affinity of RNA with therapeutic drugs in treating viral diseases such as HIV and hepatitis C. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-99-3. Molecular formula: C46H57F2N8O8P. Mole weight: 918.96.
Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl) is an exquisite biomedical compound, renowned for its antiviral prowess. It diligently aids to study pernicious viral infections such as hepatitis C and herpes simplex. CAS No. 2299278-41-2. Molecular formula: C37H42N6O7. Mole weight: 682.77.
Guanosine, 3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-methyl-1-oxopropyl)-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an indispensable compound employed extensively in the realm of biomedical exploration, specifically in nucleic acid synthesis. This remarkable compound acts as a modulated foundational unit in the paradigm of solid-phase DNA synthesis, consequently enabling the assimilation of aforementioned guanosine variant into the very fabric of DNA filaments. By virtue of its distinctive phosphoramidite structure, this exemplary specimen facilitates focused inquiry into precise DNA modifications. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-2-isobutyramido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-14-9. Molecular formula: C46H59N8O8P. Mole weight: 882.98.
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