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| Product | Description | |
|---|---|---|
| 2'-O-Methylguanosine | 2'-O-Methylguanosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2140-71-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C11H15N5O5. US Biological Life Sciences. |  Worldwide |
| 2'-O-Methylguanosine | It is a guanine nucleoside analogue that is used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA virus polymerases. Synonyms: Guanosine, 2'-O-methyl-; 2'-O-Methyl Guanosine; O2'-Methylguanosine; 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-amino-9-(2-O-methyl-beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 2140-71-8. Molecular formula: C11H15N5O5. Mole weight: 297.27. |  |
| 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt | 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery. Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methylguanosine 5'-monophosphate; [(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methyl dihydrogen phosphate. Grades: ≥ 95%. CAS No. 24121-01-5. Molecular formula: C11H16N5O8P. Mole weight: 377.25. | |
| 2'-O-Methylguanosine 5'-triphosphate | 2'-O-Methylguanosine 5'-triphosphate is a vital biomolecule extensively utilized in diverse biomedical applications, serving as an essential substrate for RNA research and development and modification. Notably, this compound finding extensive application in research endeavors aimed at unraveling the intricate mechanisms underlying RNA metabolism, RNA splicing, and RNA editing. Synonyms: 2'-O-Methyl-GTP; 2'-O-methylguanosine 5'-(tetrahydrogen triphosphate); [[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; 6H-Purin-6-one, 2-amino-1, 9-dihydro-9-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-2-O-methyl-b-D-ribofuranosyl]-; Guanosine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-. Grades: ≥97% by HPLC. CAS No. 61556-44-3. Molecular formula: C11H18N5O14P3. Mole weight: 537.21. | |
| 2'-O-Methylguanosine 5'-triphosphate lithium salt | 2'-O-Methylguanosine 5'-triphosphate lithium salt, a fundamental biomedical agent utilized in the therapeutic management of diverse ailments, assumes a pivotal role as a reagent of paramount importance in scientific investigations, thereby expediting the fabrication of altered RNA species. Notably, this compound finds utility in the formulation of antiviral medicinal compounds, specifically aimed at RNA-based viruses encompassing HIV, influenza, and hepatitis C. Moreover, it exerts a profound impact on the exploration and comprehension of RNA's intricate architecture, functionality, and interplays within the biomedical domain. Synonyms: 2'-O-Me-GTP. Molecular formula: C10H18N3O14P3·xLi. Mole weight: 497.18 (free acid). | |
| 2'-O-Methylguanosine-5'-triphosphate sodium salt | 2'-O-Methylguanosine-5'-triphosphate sodium salt is a vital compound extensively utilized in the biomedical field. It is a modified nucleotide analogue that can be incorporated into RNA molecules during transcription. This compound plays a crucial role in RNA research, particularly in studies involving RNA modification and RNA structure determination. Additionally, it serves as a precursor in the synthesis of modified RNA probes used for detection and quantification of specific RNA sequences, providing accurate results in various molecular biology applications. Synonyms: 2'OMe-GTP Na. Molecular formula: C11H18N5O14P3·Na. Mole weight: 537.21 (free acid). | |
| 2'-O-Methylguanosine-5'-triphosphate trilithium salt | 2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities. Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15Li3N5O14P3. Mole weight: 555.00. | |
| 2'-O-Methylguanosine-5'-triphosphate trisodium salt | 2'-O-Methylguanosine-5'-triphosphate trisodium salt is a nucleotide analog with diverse applications. Its use in RNA synthesis not only increases stability but also specificity for protein binding. When utilized as a probe, it is an invaluable tool for investigating RNA structure and function. Beyond such scientific applications, this compound also boasts potential therapeutic benefits when targeting viral diseases and cancer. Synonyms: 2'-O-Me-GTP trisodium salt; Trisodium 5'-O-[ ({[ (hydroxyphosphinato) oxy]phosphinato}oxy) phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), sodium salt (1:3); sodium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grades: ≥97% by HPLC. Molecular formula: C11H15N5Na3O14P3. Mole weight: 603.15. | |
| 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methylguanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] | Cas No. 128219-77-2. | |
| 5'-O-DMT-2'-O-methylguanosine | 5'-O-DMT-2'-O-methylguanosine, a nucleoside analogue, finds its purpose in biomedical research due to its potential antiviral activity against RNA viruses, an area of significant scientific interest. Its inhibitory role in the replication of notorious viruses such as Zika virus and hepatitis C virus warrants further academic study. Synonyms: 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine; 5'-O-DMT-2'-O-methyl-D-guanosine. Grades: ≥ 98% (HPLC). CAS No. 103285-24-1. Molecular formula: C32H33N5O7. Mole weight: 599.65. | |
| 5'-O-DMT-2'-O-methylguanosine | 5'-O-DMT-2'-O-methylguanosine. Group: Biochemicals. Alternative Names: 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| 5'-O-DMT-N2- (4-isopropyl phenoxyacetyl) -2'-O-methylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2- (4-isopropyl phenoxyacetyl) -2'-O-methylguanosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite is a highly specialized compound used in biomedical research for the synthesis of modified RNA strands. It functions as a phosphoramidite reagent for the site-specific incorporation of 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine during oligonucleotide synthesis. This modified RNA guanosine derivative is particularly valuable for investigating the role of specific RNA sequences and structures in various biological processes and diseases. Synonyms: 2'-OMe-iPr-Pac-G phosphoramidite; 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methyl-D-guanosine 3'-CE phosphoramidite. Grades: 97%. Molecular formula: C52H62N7O10P. Mole weight: 976.09. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine | 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine, a remarkable antiviral agent employed in advanced biomedical investigations, defies viral replication across diverse strains, such as the treacherous influenza and herpes simplex virus. Equally significant, this compound boasts unrivaled eminence in probing RNA biology and delineating protein synthesis intricacies. Scientific affluence beckons its application, impelling groundbreaking inquiries exploring viral replication mechanisms and pioneering antiviral therapies. Synonyms: N2-Isobutyryl-5'-O-DMT-2'-O-methyl-D-guanosine. Grades: ≥ 98% (HPLC). CAS No. 114745-26-5. Molecular formula: C36H39N5O8. Mole weight: 669.74. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine | 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine. Group: Biochemicals. Alternative Names: N2-Isobutyryl-5'-O-DMT-2'-O-methyl-D-guanosine. Grades: Highly Purified. CAS No. 114745-26-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C36H39N5O8. US Biological Life Sciences. | Worldwide |
| 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 251647-55-9,150780-67-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C45H56N7O9P. US Biological Life Sciences. | Worldwide |
| N1,N2-Dimethyl-2'-O-methylguanosine | N1,N2-Dimethyl-2'-O-methylguanosine, a pivotal component in biomedicine, elucidates its paramountcy in diverse pathological conditions, particularly within the domain of antiviral investigation. This compound manifests noteworthy antiviral efficacy against distinct viral variants, thereby captivating interest in medicinal exploration for mitigating viral afflictions. Grades: ≥95%. CAS No. 2305416-05-9. Molecular formula: C13H19N5O5. Mole weight: 325.32. | |
| N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite | N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite | N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a vital component used in the biomedical industry for synthesizing RNA molecules. This product plays a key role in producing modified RNA molecules for research and therapeutic purposes. It enables the introduction of N2-acetyl and 2'-O-methyl groups into the guanosine structure, enhancing the stability and functionality of RNA. These modified RNA molecules find applications in studying mRNA translation, RNA-protein interactions, and as potential therapeutics for various diseases. Molecular formula: C43H52N7O9P. Mole weight: 841.89. | |
| N2-DMF-2'-O-methylguanosine | N2-DMF-2'-O-methylguanosine, an indispensable biomedical resource, showcases remarkable efficacy in combating targeted illnesses. Its distinctive composition as a modified nucleoside endows it with unparalleled potential in countering RNA viruses. Addressing the pressing need for effective antiviral treatments, especially for respiratory syncytial virus (RSV) and influenza, this compound serves as a pivotal asset in formulating groundbreaking therapies. Synonyms: N2-[(dimethylamino)methylidene]-2'-O-methyl-D-guanosine; N2-DMF-2'-O-methyl-D-guanosine; N2-DMF-2'-OMe-rG; Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-; N-(Dimethylaminomethylene)-2'-O-methylguanosine. Grades: ≥97% by HPLC. CAS No. 183737-04-4. Molecular formula: C14H20N6O5. Mole weight: 352.35. | |
| N2-DMF-2'-O-methylguanosine | N2-DMF-2'-O-methylguanosine. Group: Biochemicals. Alternative Names: N2-[ (dimethylamino) methylidene]-2'-O-methyl-D-guanosine. Grades: Highly Purified. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| N2-DMF-5'-O-DMT-2'-O-methylguanosine | N2-DMF-5'-O-DMT-2'-O-methylguanosine, a compound of utmost importance in the realm of biomedicine, exhibits profound implications in addressing a myriad of ailments, such as cancer, viral infections, and neurological disorders. By virtue of its efficacy as an antiviral and anticancer agent, this valuable substance adeptly thwarts viral replication and disrupts malignant cellular proliferation. Synonyms: N2-[(Dimethylamino)methylidene]-5'-O-DMT-2'-O-methyl-D-guanosine; N2-DMF-5'-O-DMT-2'-O-methyl-D-guanosine. Grades: ≥ 98% (HPLC). CAS No. 128219-76-1. Molecular formula: C35H38N6O7. Mole weight: 654.71. | |
| N2-DMF-5'-O-DMT-2'-O-methylguanosine | N2-DMF-5'-O-DMT-2'-O-methylguanosine. Group: Biochemicals. Alternative Names: N2-[ (Dimethylamino) methylidene]-5'-O-DMT-2'-O-methyl-D-guanosine. Grades: Highly Purified. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite | N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite | N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a highly intricate compound that holds immense significance within the realm of the biomedical industry. Through its profound involvement in the synthesis of altered oligonucleotides and nucleic acid-based therapeutics, its indispensability becomes evident. This paramount entity assumes a pivotal role in the intricate process of devising and formulating therapeutic agents targeting specific diseases, encompassing viral infections, genetic disorders, and cancer. Synonyms: N2-DMF-5'-O-DMT-2'-O-methyl-D-guanosine 3'-CE phosphoramidite. Grades: 98%. Molecular formula: C44H55N8O8P. Mole weight: 854.95. | |
| N2-iso-Butyroyl-3'-O-methylguanosine | N2-iso-Butyroyl-3'-O-methylguanosine - a valuable tool for biomedicine exploration. This organic compound finds frequent utility in mRNA synthesis, the development of capping analogs and high-affinity RNA aptamers. Its worth extends beyond these applications, with capabilities to examine structural and functional elements of mRNA capping enzymes. Synonyms: Guanosine, 3'-O-methyl-N-(2-methyl-1-oxopropyl)-; N-(9-((2R,3R,4S,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide. Grades: ≥95%. CAS No. 160107-07-3. Molecular formula: C15H21N5O6. Mole weight: 367.36. | |
| N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-Methylguanosine | N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-Methylguanosine is an intriguing compound widely employed, showcasing immense application in studying a multitude of ailments such as cancer and virus infections. Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-; N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hydroxy-4-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide. Grades: ≥95%. CAS No. 103285-33-2. Molecular formula: C36H39N5O8. Mole weight: 669.72. | |
| N2-Isobutyryl-2'-O-methylguanosine | N2-Isobutyryl-2'-O-methylguanosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| N2-Isobutyryl-2'-O-methylguanosine | N2-Isobutyryl-2'-O-methylguanosine (N2-IBU-2'-OME-RG) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 63264-29-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-21286. |  |
| N2-[(N,N-Dimethyl)amino]methylene-N1-methyl-2'-O-methylguanosine | N2-[(N,N-Dimethyl)amino]methylene-N1-methyl-2'-O-methylguanosine, a chemical compound widely employed in biomedical research, demonstrates intriguing antiviral properties, rendering it a focal point of investigation for potential RNA virus treatments. Grades: ≥95%. CAS No. 2305416-07-1. Molecular formula: C15H22N6O5. Mole weight: 366.37. | |
| N2-Phenoxyacetyl-2'-O-methylguanosine | N2-Phenoxyacetyl-2'-O-methylguanosine is a potent antiviral compound used to studying RNA viruses, including influenza and hepatitis. Through its mechanism of action, this product inhibits viral replication and enhances host antiviral responses. Synonyms: N2-Phenoxyacetyl-2'-O-methyl-D-guanosine. Molecular formula: C19H21N5O7. Mole weight: 431.41. | |
| N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite | N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite is a vital tool in the biomedical industry that aids in the synthesis of modified RNA molecules. It is utilized to introduce specific modifications into RNA sequences, enabling researchers to explore the functional roles of such nucleotides in various cellular processes. Synonyms: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-methoxypurin-2-yl]acetamide; N-Acetyl-5'-o-(4,4-dimethoxytrityl)-2'-o-[(tert-butyl)dimethylsilyl]-6'-o-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; N-Acetyl-5/'-O-(4,4-dimethoxytrityl)-2/'-O-[(tert-butyl)dimethylsilyl]-6/'-O-methylguanosine-3/'-(2-. CAS No. 153248-58-9. Molecular formula: C49H66N7O9PSi. Mole weight: 956.15. | |
| N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite | N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite, a highly indispensable asset in the realm of biomedicine, is extensively employed as a foundational component for nucleic acid synthesis, predominantly in the domain of RNA investigational studies. This remarkable resource facilitates meticulous RNA sequence customization and delineation, leading to a comprehensive comprehension of RNA's intricate constitution, operational mechanism, and its pivotal association with ailments such as cancer and viral infections. Synonyms: DMT-2'O-Methyl-rG(tac) Amidite; DMT-2'O-Methyl-rG(tac) Phosphoramidite. Molecular formula: C53H64N7O10P. Mole weight: 990.09. | |
| 1,2'-O-Dimethylguanosine | It is a dimethyl analogue of Guanosine, a purine nucleoside and a novel influenza neuraminidase inhibitor. Synonyms: N1,2'-O-dimethylguanosine; Guanosine, 1-methyl-2'-O-methyl-; 1-Methyl-2'-O-methylguanosine; 2'-O-Methyl-1-methylguanosine. Grades: ≥95%. CAS No. 73667-71-7. Molecular formula: C12H17N5O5. Mole weight: 311.29. | |
| 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase | Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that catalyses the formation of 2'-O-methylguanosine2922, a universally conserved position of the catalytic center of the ribosome that is essential for translation. 2'-O-Methylguanosine2922 is formed at a later stage of the processing, during the maturation of of the 27S pre-rRNA. In absence of snR52, Spb1p can also catalyse the formation of uridine2921. Group: Enzymes. Synonyms: Spb1p (gene name); YCL054W (gene name). Enzyme Commission Number: EC 2.1.1.167. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1764; 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase; EC 2.1.1.167; Spb1p (gene name); YCL054W (gene name). Cat No: EXWM-1764. |  |
| 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside | 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication. Synonyms: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 6-chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine. Grades: ≥95%. CAS No. 194034-59-8. Molecular formula: C11H14ClN5O4. Mole weight: 315.71. | |
| 2'-OMe-dmf-G-CE Phosphoramidite | 2'-OMe-dmf-G-CE Phosphoramidite, a vital compound in the biomedicine industry, is leveraged for the crucial synthesis of oligonucleotides. These tiny yet potent molecules are widely utilized in treating an array of afflictions such as cancer, viral infections, and genetic disorders. Devised to heighten the steadfastness and efficacy of oligonucleotides, our product offers patients the potential for better therapeutic outcomes. Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methylguanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grades: ≥ 98%. CAS No. 128219-77-2. Molecular formula: C44H55N8O8P. Mole weight: 854.92. | |
| 2'-OMe-G(iBu)-3'-phosphoramidite | 2'-OMe-G(iBu)-3'-phosphoramidite is the labile moiety used for synthesizing oligonucleotides. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite; 2'-OMe-ibu-G CE phosphoramidite; 5'-O-DMT-2'-O-Me-G(ibu) phosporamidite; DMT-2'-O-Me-rG(ib) amidite. Grades: ≥95%. CAS No. 150780-67-9. Molecular formula: C45H56N7O9P. Mole weight: 869.94. | |
| 2'-O-Methyl-GTP | 2'-O-Methyl-GTP is an extensively employed modified nucleotide in the biomedical research field to scrutinize RNA processing and gene expression. This outstanding nucleotide has been observed to impede cap-dependent translation, as well as disturb RNA splicing, making it a significant instrument for investigating cancer and other RNA metabolism-related ailments. Furthermore, the substrate ability of 2'-O-Methyl-GTP enables the labeling of RNA with biotin or other tags for recognition and purification, thereby amplifying its significance and versatility as a research tool. Synonyms: 2'-O-Methylguanosine-5'-Triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C11H18N5O14P3. Mole weight: 537.21. | |
| 2'-O-Methyl-N2-isobutyroylguanosine | 2'-O-Methyl-N2-isobutyroylguanosine is a biomedicine used in the reserch of certain diseases, including cancer. It acting as an antineoplastic compound and exhibiting potent activity against specific tumor cells. Its mechanism of action involves inhibiting cell growth and inducing apoptosis. Synonyms: N2-Isobutyryl-2'-O-methylguanosine; N2-Isobutyryl-2'-O-methyl-D-guanosine; IBU-2'-OME-G; N2-isobutyryl-O2'-methyl-guanosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-methyl-N-(2-methyl-1-oxopropyl)-. Grades: ≥95%. CAS No. 63264-29-9. Molecular formula: C15H21N5O6. Mole weight: 367.36. | |
| 2'-O-Methyl-N2,N2-dimethyl-guanosine | It is a modified nucleoside in tRNA of hyperthermophilic archaebacteria. Synonyms: N2,N2,2'-O-Trimethylguanosine; Guanosine, N,N-dimethyl-2'-O-methyl-; N,N,2'-O-Trimethylguanosine; N,N-Dimethyl-2'-O-methylguanosine. Grades: ≥95%. CAS No. 113886-73-0. Molecular formula: C13H19N5O5. Mole weight: 325.32. | |
| 3'-O-Methylguanosine | 3'-O-Methylguanosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 10300-27-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C11H15N5O5. US Biological Life Sciences. | Worldwide |
| 3'-O-Methylguanosine | 3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Synonyms: 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 10300-27-3. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| Lexanersen | Lexanersen is an abnormal huntingtin synthesis reducer. Synonyms: (P3'S)-2'-O-methyl-P-thioguanylyl-(3'?5')-2'-O-methyluridylyl-(3'?5')-2'-O-methylguanylyl-(3'?5')-2'-O-methylcytidylyl-(3'?5')-(P3'S)-2'-O-methyl-P-thioadenylyl-(3'?5')-(P3'S)-2'-deoxy-P-thiocytidylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'S)-2'-deoxy-P-thiocytidylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioguanylyl-(3'?5')-(P3'S)-P-thiothymidylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'R)-2'-deoxy-P-thioguanylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'S)-P-thiothymidylyl-(3'?5')-2'-O-methylguanylyl-(3'?5')-2'-O-methyladenylyl-(3'?5')-2'-O-methylguanylyl-(3'?5')-(P3'S)-2'-O-methyl-P-thioguanylyl-(3'?5')-2'-O-methylguanosine. CAS No. 2073015-40-2. Molecular formula: C206H262N85O112P19S13. Mole weight: 6726.21. | |
| N7-Methyl-3'-O-methylguanosine | N7-Methyl-3'-O-methylguanosine is a paramount compound, displaying immense application in the advancement of pharmacological compounds that specifically target RNA-dependent mechanisms. Grades: ≥95%. Molecular formula: C12H17N5O5. Mole weight: 311.30. | |
| O6-Methylguanosine | It is a guanine derivative that acts as a modulator of GTPases and modulator-resistant enzymes. Synonyms: 6-O-Methylguanosine; 2-Amino-6-methoxy-9-β-D-ribofuranosyl-9H-purine; 2-Amino-6-methoxypurine Ribonucleoside; 6-Methoxy-9-β-D-ribofuranosyl-9H-purin-2-amine; NSC 66381; O-Methylguanosine; (2R,3R,4S,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 7803-88-5. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| Rp-2'-O-Me-GTP-α-S | Rp-2'-O-Me-GTP-α-S is a phosphorothioate analogue of GTP. Synonyms: 2'-O-Methylguanosine-5'-O-(1-thiotriphosphate), Rp-isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143028-96-0. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid). | |
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