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| Product | Description | |
|---|---|---|
| 2-APB | 2-APB, a transient receptor potential (TRP) activator for TRPV1, TRPV2, and TRPV3, could probably be used against diseases caused by hypersensitivity and temperature misregulation. Synonyms: 2-Aminoethoxydiphenylborane. Grades: ≥98% by HPLC. CAS No. 524-95-8. Molecular formula: C14H16BNO. Mole weight: 225.10. |  |
| 2-APB | A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42uM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10uM) and inhibits it at higher concentrations (up to 50uM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes. Group: Biochemicals. Grades: Highly Purified. CAS No. 524-95-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| 2-APB (2-Aminoethyl diphenyl borate, Diphenylboric acid 2-aminoethyl ester, Diphenylborinic acid) | A membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP?) receptor antagonist (IC50= 42uM). Group: Biochemicals. Alternative Names: 2-Aminoethyl diphenyl borate, Diphenylboric acid 2-aminoethyl ester, Diphenylborinic acid. Grades: Purified. CAS No. 524-95-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (2-Aminoethoxy)diphenylborane | (2-Aminoethoxy)diphenylborane. Group: Salt. Alternative Names: 2,2-DIPHENYL-1,3,2-OXAZA-BOROLIDINE INTERNAL SALT; 2-APB; 2-AMINOETHYL DIPHENYL BORATE; 2-AMINOETHYL DIPHENYLBORINATE; (2-AMINOETHOXY)DIPHENYLBORANE; 2-AMINOETHOXYDIPHENYLBORATE; BETA-AMINOETHYL DIPHENYLBORINATE; DIPHENYLBORIC ACID 2-AMINOETHYL ESTER. CAS No. 524-95-8. Product ID: 2-diphenylboranyloxyethanamine. Molecular formula: 225.1g/mol. Mole weight: C14H16BNO. B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN. InChI=1S/C14H16BNO/c16-11-12-17-15 (13-7-3-1-4-8-13) 14-9-5-2-6-10-14/h1-10H, 11-12, 16H2. BLZVCIGGICSWIG-UHFFFAOYSA-N. >98 %. |  |
| 2-Aminoethyl diphenylborinate | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor ( IP3R ). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-APB. CAS No. 524-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009724. |  |
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