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| Product | Description | |
|---|---|---|
| 2-(2-Heptynylthio)-phenol acetate | 2-(2-Heptynylthio)-phenol acetate. Group: Biochemicals. Alternative Names: APHS. Grades: Highly Purified. CAS No. 209125-28-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H18O2S. US Biological Life Sciences. |  Worldwide |
| APHS | APHS is a specific and covalent COX-2 inhibitor with neuroprotective effects. COX-2 is a prostaglandin (PG) synthetase overexpressed in colorectal cancer (CRC) and has pleiotropic cancer-promoting effects. APHS modifies COX-2 by acetylating the active site (serine 516), thereby inhibiting prostaglandin production. The neuroprotective activity of APHS is inhibited by prostaglandin E2. APHS also co-inhibits the WNT pathway, an anti-tumor mechanism in addition to COX-2 inhibition [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 209125-28-0. Pack Sizes: 1 mg (38.11 mM * 100 μL in Methyl acetate); 5 mg (38.11 mM * 500 μL in Methyl acetate); 10 mg (38.11 mM * 1 mL in Methyl acetate). Product ID: HY-129284. |  |
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