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| Product | Description | |
|---|---|---|
| GC 1 | GC 1. Group: Biochemicals. Grades: Purified. CAS No. 211110-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Sobetirome | Sobetirome (GC-1) is a thyroid hormone receptor β ( TRβ )-specific agonist which bind selectively to TRβ-1 with an EC 50 of 0.16 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GC-1; QRX-431. CAS No. 211110-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14823. |  |
| Sobetirome | Sobetirome Inhibitor. Uses: Scientific use. Product Category: T5313. CAS No. 211110-63-3. |  |
| Sobetirome | Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol through activation of liver TRbeta without stimulating cardiac function through TRalpha activation in the heart. The tissue selective thyromimetic properties of sobetirome have been demonstrated in numerous animal models, which led to its clinical development as a novel cholesterol-lowering agent. Treatment of hypercholestemia obesity, and thyroid proliferative disorders. Synonyms: GC-1; GC1; GC 1; QRX-431; QRX 431; QRX431; Sobetirome. Grades: >98%. CAS No. 211110-63-3. Molecular formula: C20H24O4. Mole weight: 328.4. |  |
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