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| Product | Description | |
|---|---|---|
| 22(R)-Hydroxycholesterol | 22(R)-Hydroxycholesterol (Narthesterol) is an endogenous LXR agonist. 22(R)-Hydroxycholesterol (Narthesterol) can be used for tangier disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Narthesterol. CAS No. 17954-98-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-116969. |  |
| 22(R)-Hydroxycholesterol | ?98%. Group: Fluorescence/luminescence spectroscopy. |  |
| 22-alpha-Hydroxy Cholesterol | 22α-Hydroxy Cholesterol is the 22R-metabolite of Cholesterol. 22-Hydroxycholesterol inhibits chemokine receptor activity. Synonyms: (3β,22R)-Cholest-5-ene-3,22-diol; (20S,22R)-Cholest-5-ene-3β,22-diol; (22R)-22-Hydroxycholesterol; (22R)-Cholest-5-ene-3β,22-diol; (22R)-Hydroxycholesterol; 22α-Hydroxycholesterol; Cholest-5-ene-3β,22(R)-diol; Narthesterol. Grades: > 95%. CAS No. 17954-98-2. Molecular formula: C27H46O2. Mole weight: 402.67. |  |
| 22(S)-Hydroxy cholesterol | 22(S)-Hydroxy cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). Synonyms: cholest-5-ene-3β,22(S)-diol; 22(S)-Hydroxycholesterol; 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol; 22β-Hydroxy Cholesterol; (3β,22S)-Cholest-5-ene-3,22-diol; (20S,22S)-Cholest-5-ene-3β,22-diol; (22S)-22-Hydroxycholesterol; (22S)-Cholest-5-ene-3β,22-diol; (22β)-Hydroxycholesterol; Narthesterol. Grades: ≥95%. CAS No. 22348-64-7. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| 25/26-hydroxycholesterol 7α-hydroxylase | A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.29. CAS No. 149316-80-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0926; 25/26-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.29; 149316-80-3; 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Cat No: EXWM-0926. |  |
| 2-Bromoethylcyclopropane | 2-Bromoethylcyclopropane is used as a reagent to synthesize 22-Hydroxycholesterol (H918010) derivatives, compounds that act as serum cholesterol lowering agents. 2-Bromoethylcyclopropane is also used to prepare pyridazinones, compounds that act as cyclooxygenase 2-inhibitors (they possess anti-inflammatory and antiangiogenic effects). Group: Biochemicals. Grades: Highly Purified. CAS No. 36982-56-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C5H9Br. US Biological Life Sciences. |  Worldwide |
| 2-Cyclopropylethanol | 2-Cyclopropylethanol is used as a reagent to synthesize 22-Hydroxycholesterol (H918010) derivatives, compounds that act as serum cholesterol lowering agents. 2-Bromoethylcyclopropane is also used to prepare pyridazinones, 2-Cyclopropylethanol is also used to synthesize potent 15-Hydroxyprostaglandin dehydrogenase inhibitors, which ultimately minimize excessive scarring of wounds. Group: Biochemicals. Grades: Highly Purified. CAS No. 2566-44-1. Pack Sizes: 2.5g, 5g. Molecular Formula: C5H10O, Molecular Weight: 86.13. US Biological Life Sciences. | Worldwide |
| 5-Cholesten-3β,22(R)-diol | 5-Cholesten-3β,22(R)-diol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 22(R)-HYDROXYCHOLESTEROL; 22BETA-HYDROXYCHOLESTEROL; Narthesterol; 22BF-HYDROXYCHOLESTEROL; 22R-OHC; 22(R)-Hydroxycholesterol. Product Category: Steroidal Compounds. CAS No. 17954-98-2. Molecular formula: C27H46O2. Mole weight: 402.65. Purity: 0.98. IUPACName: (22R)-22-hydroxycholesterol. Density: 1.03 g/cm³. Product ID: ACM17954982. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 5-Cholesten-3β,22(S)-diol | 5-Cholesten-3β,22(S)-diol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 22S-hydroxycholesterol; 22(R)-HYDROXYCHOLESTEROL; beta2-Solamargine; 22(S)-Hydroxycholesterol. Product Category: Steroidal Compounds. CAS No. 22348-64-7. Molecular formula: C27H46O2. Mole weight: 402.65. Purity: 0.95. IUPACName: (8S,9S,10R,13S,14S,17R)-17-[(2S,3R)-3-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)CCC(C(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)O. Product ID: ACM22348647. Alfa Chemistry ISO 9001:2015 Certified. | |
| SR3335 | The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It has no effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor &alpha. SR 3335 evokes RORα-dependent effects both in vitro and in vivo, altering gene expression as well as gluconeogenesis. Synonyms: ML-176; SR 3335; SR-3335; ML176; ML 176. Grades: >98%. CAS No. 293753-05-6. Molecular formula: C13H9F6NO3S2. Mole weight: 405.34. | |
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