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1-NM-PP1 1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively). Synonyms: 1NM-PP1; 1NM PP1; 1NMPP1l PP1 analog II. CAS No. 221244-14-0. Molecular formula: C20H21N5. Mole weight: 331.41424. BOC Sciences 10
4-Amino-1-tert-butyl-3- (1’-naphthylmethyl) pyrazolo[3, 4-d]pyrimidine (1-NMPP1, 1-NM-PP1) A highly potent (IC50=4.3 nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase. Group: Biochemicals. Alternative Names: 1-(1,1-Dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-NM-PP1. Grades: Highly Purified. CAS No. 221244-14-0. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C20H21N5, Molecular Weight: 331.41. US Biological Life Sciences. USBiological 1
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