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A22 hydrochloride A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant. A22 inhibition of MreB disrupts the bacterial actin cytoskeleton, which can cause an increase in cell permeability and altered transport. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MreB Perturbing Compound A22; A22 hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 22816-60-0. Molecular formula: C8H9Cl3N2S. Mole weight: 271.58. Purity: >98%. IUPACName: S-(3,4-Dichlorobenzyl)isothiourea hydrochloride. Canonical SMILES: N=C(N)SCC1=CC=C(Cl)C(Cl)=C1.[H]Cl. Product ID: ACM22816600-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
MreB Perturbing Compound A22 MreB perturbing compound A22 is a benzylisothiourea compound that rapidly and reversibly perturbs MreB. It converts normal bacterial rod-shape cells to coccoid cells. It interferes with chromosome segregation in C. crescentus by blocking the binding of MreB to chromosomes. Synonyms: 2-(3,4-Dichloro-benzyl)-isothiourea hydrochloride; S-(3,4-Dichlorobenzyl)isothiourea HCl; 3,4-dichlorobenzyl carbamimidothioate hydrochloride. Grades: ≥95%. CAS No. 22816-60-0. Molecular formula: C8H8Cl2N2S·HCl. Mole weight: 271.6. BOC Sciences 9

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