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Hyperforin DCHA Key constituent of St. John's wort. Shows properties of potential pharmacological interest, including anti-bacterial, anti-malarial, anti-inflammatory, anti-cancer and anti-angiogenic effects. Anti-depressant and anxiolytic compound. Specific activator of TRPC6 channels. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Activator of the pregnane X receptor (PXR). Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Potential anti-Alzheimer compound. Potent SIRT1 (sirtuin 1) and SIRT2 (sirtuin 2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 238074-03-8. Pack Sizes: 500ug, 1mg. Molecular Formula: C35H51O4 C12H24N. US Biological Life Sciences. USBiological 3
Worldwide
Hyperforin DCHA (5-hydroxy-6R-methyl-1R, 3, 7S-tris(3-methyl-2-butenyl)-5S-(2-methyl-1-oxopropyl)-6R-(4-methyl-3-pentenyl)-bicyclo[3.3.1]non-3-ene-2,9-dione, DHCA) Displays a variety of biological activities including anti-bacterial, anti-inflammatory, anticancer and anti-angiogenic effects. Also acts as an antidepressant and anxiolytic agent. Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and hepatic drugs metabolism. Inhibits the re-uptake of neurotransmitters in synapses (serotonin, norepinephrine, dopamine, GABA, glutamate). Also acts as a potent SIRT1 and SIRT2 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 238074-03-8. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. USBiological 4
Worldwide
Hyperforin dicyclohexylammonium salt Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca 2+ levels by activating Ca 2+ -conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin dicyclohexylammonium salt modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hyperforin DCHA. CAS No. 238074-03-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-116330A. MedChemExpress MCE
Hyperforin dicyclohexylammonium salt Hyperforin is a principal ingredient of Hypericum perforatum (St. John's wort). Hyperforin activates TRPC6 channel to inhibit the reuptake of serotonin, suggesting its potential use as an antidepressant. It also exhibits antibacterial effects. Synonyms: Hyp-DCHA; Hyperforin-DCHA; Hyperforin DCHA. Grades: ≥97%. CAS No. 238074-03-8. Molecular formula: C35H52O4·C12H23N. Mole weight: 718.1. BOC Sciences 10

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