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| Product | Description | |
|---|---|---|
| 24,25-Epoxycholesterol | 24,25-Epoxycholesterol is sterol found in red alga Rissoella verruculosa and Galaxaura marginata and exhibits cytotoxicity toward several cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 72542-49-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences. |  Worldwide |
| (24S)-24,25-Epoxycholesterol | (24S)-24,25-Epoxycholesterol is a derivative of 4 β-Hydroxy Cholesterol (H917980), a metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker. Group: Biochemicals. Grades: Highly Purified. CAS No. 77058-74-3. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences. | Worldwide |
| 25/26-hydroxycholesterol 7α-hydroxylase | A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. |  |
| 25/26-hydroxycholesterol 7α-hydroxylase | A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.29. CAS No. 149316-80-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0926; 25/26-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.29; 149316-80-3; 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Cat No: EXWM-0926. | |
| 5-Cholesten-24(S),25-epoxy-3β-ol | 5-Cholesten-24(S),25-epoxy-3β-ol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-4-[(2S)-3,3-dimethyloxiran-2-yl]butan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; 24S,25-epoxy-cholest-5-en-3beta-ol; 24,25-epoxy-cholesterol; (24S)-24,25-epoxycholesterol; 24S,25-epoxy-cholesterol; 24(R),25-epoxycholesterol. Product Category: Steroidal Compounds. CAS No. 77058-74-3. Molecular formula: C27H44O2. Mole weight: 400.64. Purity: 95%+. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-4-[(2S)-3,3-dimethyloxiran-2-yl]butan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(CCC1C(O1)(C)C)C2CCC3C2(CCC4C3CC=C5C4(CCC(C5)O)C)C. Density: 1.05. Product ID: ACM77058743. Alfa Chemistry ISO 9001:2015 Certified. |  |
| MM0299 | MM0299 is an inhibitor for lanosterol synthase (LSS) with an IC50 of 2.2 ?M. MM0299 inhibits cell proliferation of Mut6 with an IC50 of 0.0182 ?M, through generation of 24(S),25-epoxycholesterol (EPC) and the depletion of cellular cholesterol[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 474255-10-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160972. |  |
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