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5?-Deoxy-5?-methylthioadenosine - CAS 2457-80-9 A cell-permeable, reversible, and ATP-competitive naturally-occurring co-product of polyamine biosynthesis that acts as an endogenous substrate of methylthioadenosine phosphorylase (MTAP). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
5'-Deoxy-5'-(methylthio)adenosine 5?-Deoxy-5?-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5?-methyl thioadenosine phosphoryl ase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Methylthioadenosine is used in studies on bacterial quorum sensing pathways that envolve enzymes such as 5?-Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN). Group: Biochemicals. Alternative Names: 5'-S-Methyl-5'-thioadenosine; 5'-(Methylthio)-5'-deoxyadenosine; 5'-(Methylthio)adenosine; 5'-Deoxy (methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine; 5'-S-Methylthioadenosine; NSC 335422; Vitamin L2; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio- β-D-ribofuranose. Grades: Highly Purified. CAS No. 2457-80-9. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
Worldwide
5'-Methylthioadenosine 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis [1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-(Methylthio)-5'-deoxyadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine. CAS No. 2457-80-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-16938. MedChemExpress MCE

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