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| Product | Description | |
|---|---|---|
| Laquinimod | Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215062. CAS No. 248281-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13010. |  |
| Laquinimod | Laquinimod, also known as, is an experimental immunomodulator developed by Active Biotech and Teva. It is being investigated as an oral treatment for multiple sclerosis (MS). Laquinimod is the successor of Active Biotech's failed experimental immunomodulator linomide. Laquinimod seems to be able to reduce the MS disease activity on MRI. In 2011, Teva announced its clinical trials involving laquinimod had failed, being unable to significantly reduce relapses into MS among patients beyond a placebo. However, the final results of above-mentioned phase III trial proved oral laquinimod administered once daily slowed the progression of disability and reduced the rate of relapse in patients with relapsing-remitting multiple sclerosis. Synonyms: Laquinimod; ABR 215062; ABR215062; ABR-215062. ABR-215062; SAIK-MS; TV-5600; TV5600; TV 5600. CAS No. 248281-84-7. Molecular formula: C19H17ClN2O3. Mole weight: 356.8. |  |
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