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| Product | Description | |
|---|---|---|
| 27-hydroxycholesterol | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| 27-Hydroxycholesterol | 27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor. Uses: Scientific research. Group: Natural products. Alternative Names: 27-OHC. CAS No. 20380-11-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N2371. |  |
| 27-Hydroxycholesterol | 27-Hydroxycholesterol, a desmosterol metabolite found in the brain , activates LXRα (EC50= 85 nM)and LXRβ (EC50= 71 nM) in vitro. 27-HC is also an estrogen receptor partial agonist. It suppresses β-estradiol-mediated breast cancer cell proliferation in vitro. Synonyms: cholest-(25R)-5-ene-3β,27-diol; (25R)-Cholest-5-ene-3β,26-diol; 27-OHC; 5,25R-Cholesten-3beta,26-diol; (25R)-26-Hydroxycholesterol. Grade: >99%. CAS No. 20380-11-4. Molecular formula: C27H46O2. Mole weight: 402.65. |  |
| 25/26-hydroxycholesterol 7α-hydroxylase | A P-450 (heme-thiolate) protein. Unlike EC 1.14.14.26, 24-hydroxycholesterol 7α-monooxygenase, which is specific for its oxysterol substrate, this enzyme can also metabolize the oxysterols 24,25-epoxycholesterol, 22-hydroxycholesterol and 24-hydroxycholesterol, but to a lesser extent. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Enzyme Commission Number: EC 1.14.14.29. CAS No. 149316-80-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0926; 25/26-hydroxycholesterol 7α-hydroxylase; EC 1.14.14.29; 149316-80-3; 25-hydroxycholesterol 7α-monooxygenase; CYP7B1; CYP7B1 oxysterol 7α-hydroxylase; 27-hydroxycholesterol 7-monooxygenase; 27-hydroxycholesterol 7α-hydroxylase; cholest-5-ene-3β,25-diol,NADPH:oxygen oxidoreductase (7α-hydroxylating); 25-hydroxycholesterol 7α-hydroxylase. Cat No: EXWM-0926. |  |
| (3β,25R)-Hydroxy-5-cholestenoic acid | (3β,25R)-Hydroxy-5-cholestenoic acid is a metabolite of 27-hydroxycholesterol. Synonyms: Cholest-5-en-26-oic acid, 3-hydroxy-, (3β,25R)-; (3β,25R)-3-Hydroxycholest-5-en-26-oic acid; (2R,6R)-6-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptanoic acid; (25R)-3beta-hydroxycholest-5-en-26-oic acid. Grade: >99%. CAS No. 56845-87-5. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| 7α,27-Dihydroxycholesterol | 7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC). Uses: Scientific research. Group: Signaling pathways. CAS No. 4725-24-0. Pack Sizes: 1 mg. Product ID: HY-W414548. | |
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