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| Product | Description | |
|---|---|---|
| 3-Amino-1,2,4-benzotriazine 1,4-dioxide | 3-Amino-1,2,4-benzotriazine 1,4-dioxide. Group: Biochemicals. Alternative Names: 1,2,4-Benzotriazin-3-amine 1,4-dioxide; SR 259075; SR 4233. Grades: Highly Purified. CAS No. 27314-97-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C7H6N4O2. US Biological Life Sciences. |  Worldwide |
| 3-Amino-1,2,4-benzotriazine-1,4-dioxide (SR-4233, Tirapazamine) | Bioreductive anticancer agent. Selectively toxic to cells under hypoxic conditions. An antineoplastic. Group: Biochemicals. Alternative Names: SR-4233, Tirapazamine. Grades: Highly Purified. CAS No. 27314-97-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Tirapazamine | Tirapazamine is a benzotriazine di-N-oxide with potential antineoplastic activity. Tirapazamine is selectively activated by multiple reductases to form free radicals in hypoxic cells, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. This agent also sensitizes hypoxic cells to ionizing radiation and inhibits the repair of radiation-induced DNA strand breaks via inhibition of topoisomerase II. Check for active clinical trials or closed clinical trials using this agent. Synonyms: US brand name: Tirazone. Code names: SR 4233. WIN 59075. SR-259075, NSC-130181, Win-59075, SR-4233. Grades: 0.98. CAS No. 27314-97-2. Molecular formula: C7H6N4O2. Mole weight: 178.15. |  |
| Tirapazamine | Tirapazamine (SR259075) is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. Tirapazamine is an anticancer and bioreductive agent.Tirapazamine (SR259075) can enhance the cytotoxic effects of ionizing radiation in hypoxic cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR259075; SR4233; Win59075; SML 0552; SR 259075; Tirazone. CAS No. 27314-97-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-13767. |  |
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