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| Product | Description | |
|---|---|---|
| Nigericin | Nigericin Inhibitor. Uses: Scientific use. Product Category: T3092. CAS No. 28643-80-3. |  |
| Nigericin sodium salt | Antibiotic [1]. High affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+ [2, 3, 4, 7, 10]. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity [3, 6]. Disrupts membrane potential of mitochondria [2]. NLRP3/NALP3 activator. Signals through pannexin-1 to induce caspase-1 maturation and IL-1 β processing and release [5, 8, 11, 12]. Autophagy modulator [13]. Group: Biochemicals. Alternative Names: Antibiotic K 178; Helexin C; Polyetherin A; BRN 1696755; Azalomycin M; Antibiotic X-464. Grades: Highly Purified. CAS No. 28643-80-3. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Nigericin sodium salt | Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K + /H + ionophore , promoting K + /H + exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt / β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1 /GSDMD in TNBC [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 28643-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100381. |  |
| Nigericin sodium salt | Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 28643-80-3. Molecular formula: C40H67NaO11. Mole weight: 746.94. Purity: Purity >98%. Product ID: ACM28643803. Alfa Chemistry ISO 9001:2015 Certified. |  |
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