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3-Isobutyl-1-methylxanthine 3-Isobutyl-1-methylxanthine. Group: Biochemicals. Alternative Names: 3,9-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione; IBMX. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C10H14N4O2. US Biological Life Sciences. USBiological 7
Worldwide
3-Isobutyl-1-methylxanthine (IBMX) A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC50=2-50uM). Also acts as an adenosine receptor antagonist. Reported to inhibit TNF-a expression in adipocyte precursor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 250mg, 1g. US Biological Life Sciences. USBiological 4
Worldwide
IBMX IBMX. Group: Biochemicals. Grades: Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 5
Worldwide
IBMX IBMX Inhibitor. Uses: Scientific use. Product Category: T1713. CAS No. 28822-58-4. TARGETMOL CHEMICALS
IBMX IBMX is an inhibitor of cAMP and cGMP phosphodiesterases. IBMX was shown to promote differentiation of 3T3-L1 cells in combination with insulin and dexamethasone. It also induces neural transdifferentiation of mesenchymal stem cells (MSCs) through downregulation of the NRSF. Uses: Phosphodiesterase inhibitors. Synonyms: 3-Isobutyl-1-methylxanthine; isobutylmethylxanthine; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione. Grades: >98%. CAS No. 28822-58-4. Molecular formula: C10H14N4O2. Mole weight: 222.24. BOC Sciences 11
IBMX (3-Isobutyl-1-methylxanthine) 3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 9
Worldwide
IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3) Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity. Group: Biochemicals. Alternative Names: 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g. US Biological Life Sciences. USBiological 3
Worldwide

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