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A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC?? = 2-50 μM). Group: Fluorescence/luminescence spectroscopy.
3-Isobutyl-1-methylxanthine
3-Isobutyl-1-methylxanthine. Group: Biochemicals. Alternative Names: 3,9-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione; IBMX. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C10H14N4O2. US Biological Life Sciences.
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3-Isobutyl-1-methylxanthine (IBMX)
A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC50=2-50uM). Also acts as an adenosine receptor antagonist. Reported to inhibit TNF-a expression in adipocyte precursor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
Worldwide
IBMX
IBMX. Group: Biochemicals. Grades: Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences.
IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 ?M for PDE3, PDE4 and PDE5, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine. CAS No. 28822-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-12318.
IBMX
IBMX is an inhibitor of cAMP and cGMP phosphodiesterases. IBMX was shown to promote differentiation of 3T3-L1 cells in combination with insulin and dexamethasone. It also induces neural transdifferentiation of mesenchymal stem cells (MSCs) through downregulation of the NRSF. Uses: Phosphodiesterase inhibitors. Synonyms: 3-Isobutyl-1-methylxanthine; isobutylmethylxanthine; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione. Grade: >98%. CAS No. 28822-58-4. Molecular formula: C10H14N4O2. Mole weight: 222.24.
IBMX (3-Isobutyl-1-methylxanthine)
3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences.