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3'-O-Methylguanosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 10300-27-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C11H15N5O5. US Biological Life Sciences.
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3'-O-Methylguanosine
3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis [1]. Uses: Scientific research. Group: Natural products. CAS No. 10300-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W091784.
3'-O-Methylguanosine
3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject. Synonyms: 3'-(O-Methyl) Guanosine; 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one. Grade: ≥95%. CAS No. 10300-27-3. Molecular formula: C11H15N5O5. Mole weight: 297.27.
3'-O-Methylguanosine 5'-triphosphate ammonium salt
3'-O-Methylguanosine 5'-triphosphate ammonium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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3'-O-Methylguanosine 5'-triphosphate lithium salt
3'-O-Methylguanosine 5'-triphosphate lithium salt, known for its remarkable properties, is extensively utilized in the realm of biomedicine across diverse applications. This potent compound assumes an indispensable role in the therapeutic interventions for specific ailments and is a staple in drug research and development ventures. Capitalizing on its distinctive chemical attributes, this compound has exhibited tremendous efficacy in selectively targeting pivotal enzymes and pathways associated with the advancement of maladies. Grade: ≥ 95%. Molecular formula: C11H14N5O14P3·Li4. Mole weight: 560.94.
3'-Deoxy-2'-O-methylguanosine
3'-Deoxy-2'-O-methylguanosine is a vital compound used for various applications, playing a significant role in the field of drug development and viral infections research. Additionally, it is utilized in nucleic acid research to study RNA structure and function, providing valuable insights into gene expression and regulation. Synonyms: Guanosine, 3'-deoxy-2'-O-methyl-. CAS No. 847648-36-6. Molecular formula: C11H15N5O4. Mole weight: 281.27.
5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite is a highly specialized compound used in biomedical research for the synthesis of modified RNA strands. It functions as a phosphoramidite reagent for the site-specific incorporation of 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine during oligonucleotide synthesis. This modified RNA guanosine derivative is particularly valuable for investigating the role of specific RNA sequences and structures in various biological processes and diseases. Synonyms: 2'-OMe-iPr-Pac-G phosphoramidite; 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methyl-D-guanosine 3'-CE phosphoramidite. Grade: 97%. Molecular formula: C52H62N7O10P. Mole weight: 976.09.
N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
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1,2'-O-dimethylguanosine
It is a dimethyl analogue of Guanosine, a purine nucleoside and a novel influenza neuraminidase inhibitor. Synonyms: N1,2'-O-dimethylguanosine; Guanosine, 1-methyl-2'-O-methyl-; 1-Methyl-2'-O-methylguanosine; 2'-O-Methyl-1-methylguanosine. Grade: ≥95%. CAS No. 73667-71-7. Molecular formula: C12H17N5O5. Mole weight: 311.29.
1,3'-O-Dimethylguanosine
1,3'-O-Dimethylguanosine, a nucleoside derivative, is widely applied in biomedicine, especially in gene expression and transcriptional regulation. Deriving from extensive analyses, 1,3'-O-Dimethylguanosine exhibits potential in impeding cell growth and proliferation, rendering it a prime option for varied cancer types. Synonyms: Guanosine, 1-methyl-3'-O-methyl-; N1-Methyl-3'-O-methyl guanosine; N1,3'-O-dimethylguanosine; 1-Methyl-3'-O-methylguanosine; 3'-O-Methyl-1-methylguanosine. Grade: ≥95%. CAS No. 74466-66-3. Molecular formula: C12H17N5O5. Mole weight: 311.29.
2-Amino-6-chloropurine-9-(2'-O-methyl)riboside
2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication. Synonyms: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside. Grade: ≥95%. CAS No. 194034-59-8. Molecular formula: C11H14ClN5O4. Mole weight: 315.71.
2'-OMe-dmf-G-CE Phosphoramidite
2'-OMe-dmf-G-CE Phosphoramidite, a vital compound in the biomedicine industry, is leveraged for the crucial synthesis of oligonucleotides. These tiny yet potent molecules are widely utilized in treating an array of afflictions such as cancer, viral infections, and genetic disorders. Devised to heighten the steadfastness and efficacy of oligonucleotides, our product offers patients the potential for better therapeutic outcomes. Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methylguanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; DMT-2'-O-Me-G(dmf)-CE Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-OMe-G-CE Phosphoramidite; 2'-O-Methyl Guanosine (n,n-dmf) CED phosphoramidite. Grade: ≥95%. CAS No. 128219-77-2. Molecular formula: C44H55N8O8P. Mole weight: 854.92.
2'-OMe-G(iBu)-3'-phosphoramidite
2'-OMe-G(iBu)-3'-phosphoramidite is a modified phosphoramidite designed for the synthesis of stable and efficient RNA oligonucleotides. The protective groups and modifications, such as 5'-O-DMTr, N2-isobutyryl, and 2'-O-methyl, enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in producing antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite; 2'-OMe-iBu-G CE phosphoramidite; 5'-O-DMT-2'-O-Me-G(iBu) phosporamidite; DMT-2'-O-Me-rG(iBu) amidite; N2-Isobutyryl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-Guanosine-3'-CE-Phosphoramidite. Grade: ≥95%. CAS No. 150780-67-9. Molecular formula: C45H56N7O9P. Mole weight: 869.94.
2'-O-Methylguanosine 5'-monophosphate
2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery. Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methyl-guanosine 5'-monophosphate; 2'-O-Me-GMP; 2'-O-Methylguanosine 5'-(dihydrogen phosphate). Grade: ≥95% by HPLC. CAS No. 24121-01-5. Molecular formula: C11H16N5O8P. Mole weight: 377.25.
2'-O-Methylguanosine-5'-triphosphate trilithium salt
2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities. Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grade: ≥97% by HPLC. Molecular formula: C11H15Li3N5O14P3. Mole weight: 555.00.
2'-O-Methylguanosine-5'-triphosphate trisodium salt
2'-O-Methylguanosine-5'-triphosphate trisodium salt is a nucleotide analog with diverse applications. Its use in RNA synthesis not only increases stability but also specificity for protein binding. When utilized as a probe, it is an invaluable tool for investigating RNA structure and function. Beyond such scientific applications, this compound also boasts potential therapeutic benefits when targeting viral diseases and cancer. Synonyms: 2'-O-methyl-Guanosine-5'-triphosphate, trisodium salt; 2'-O-Methylguanosine 5'-(tetrahydrogen triphosphate) trisodium salt; 2'-O-Methyl-GTP trisodium salt; 2'-O-Methylguanosine triphosphate trisodium salt; 2'-O-Me-GTP trisodium salt; Trisodium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), sodium salt (1:3); sodium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate. Grade: ≥97% by HPLC. Molecular formula: C11H15N5Na3O14P3. Mole weight: 603.15.
2'-O-Methyl-N2-isobutyroylguanosine
2'-O-Methyl-N2-isobutyroylguanosine is a biomedicine used in the reserch of certain diseases, including cancer. It acting as an antineoplastic compound and exhibiting potent activity against specific tumor cells. Its mechanism of action involves inhibiting cell growth and inducing apoptosis. Synonyms: N2-Isobutyryl-2'-O-methylguanosine; N2-Isobutyryl-2'-O-methyl-D-guanosine; IBU-2'-OME-G; N2-isobutyryl-O2'-methyl-guanosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-methyl-N-(2-methyl-1-oxopropyl)-; 2'-O-Methyl-N-(2-methyl-1-oxopropyl)guanosine. Grade: ≥95%. CAS No. 63264-29-9. Molecular formula: C15H21N5O6. Mole weight: 367.36.
2'-O-Methyl-N2,N2-dimethyl-guanosine
It is a modified nucleoside in tRNA of hyperthermophilic archaebacteria. Synonyms: N2,N2,2'-O-Trimethylguanosine; Guanosine, N,N-dimethyl-2'-O-methyl-; N,N,2'-O-Trimethylguanosine; N,N-Dimethyl-2'-O-methylguanosine. Grade: ≥95%. CAS No. 113886-73-0. Molecular formula: C13H19N5O5. Mole weight: 325.32.
3'OMe-GTP
3'OMe-GTP is a nucleoside triphosphate that has undergone modification, functioning as a surrogate for guanosine triphosphate, holding immense significance in the pursuit of comprehending RNA research and development and processing. Furthermore, owing to its utilization is an avenue paved to delve into the intricate world of RNA modifications, thereby enabling a deeper exploration into afflictions such as cancer, neurodegenerative disorders is and viral infections. Synonyms: (3'Ome)GTP; 3'-O-Methylguanosine-5'-triphosphate; 3'-O-Methylguanosine 5'-(tetrahydrogen triphosphate); 3'-O-methyl-GTP; 3'-O-Methylguanosine triphosphate. Grade: ≥95% by HPLC. CAS No. 61556-45-4. Molecular formula: C11H18N5O14P3. Mole weight: 537.21.
3'-O-Methyl-5'-guanylic acid
3-O-Methyl-5-guanylic acid is a pivotal molecule extensively employed in the realm of compound is assuming an eminent position in the research and development of sundry pharmaceutical agents and investigations concerning RNA and DNA architectures. Synonyms: 3'-OMe-GMP; 3'-O-Methylguanosine-5'-Monophosphate; 3'-O-Methylguanosine 5'-phosphate; 3'-O-Methylguanosine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate. Grade: ≥98%. CAS No. 400806-41-9. Molecular formula: C11H16N5O8P. Mole weight: 377.25.
3'-O-Methyl-GTP
3'-O-Methyl-GTP is a modified nucleotide analog that is commonly used in the biomedical industry to study the effects of post-transcriptional modifications on gene expression. This product has shown to selectively inhibit cap-dependent translation initiation by interacting with eukaryotic initiation factor 4E (eIF4E). The use of 3'-O-Methyl-GTP has been particularly valuable in cancer research where aberrant eIF4E activity has been linked to tumor formation and progression. Synonyms: 3'-O-Methylguanosine-5'-Triphosphate; 3'-o-methylguanosine 5'-(tetrahydrogen triphosphate). Grade: ≥90% by AX-HPLC. Molecular formula: C11H18N5O14P3. Mole weight: 537.21.
2'-O-Methylguanosine
It is a guanine nucleoside analogue that is used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA virus polymerases. Synonyms: 2'-(O-Methyl) Guanosine; Guanosine, 2'-O-methyl-; 2'-O-Methyl Guanosine; O2'-Methylguanosine; 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-amino-9-(2-O-methyl-beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one. Grade: ≥95%. CAS No. 2140-71-8. Molecular formula: C11H15N5O5. Mole weight: 297.27.
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